Pérez-Oliva N, Toribio J, Quiñones P A
Dermatología, Universidad de Vallodolid.
Med Cutan Ibero Lat Am. 1990;18(1):70-7.
The histopathological aspects of seborrheic keratosis have been studied in order to establish a basis to their classification upon structural morphology and cytology. The 210 seborrheic keratosis studied could be classified in several patterns among which we must point out the three most important ones: hyperkeratotic, adenoid and acanthotic. This last one can offer two very different images: uniform acanthotic (this one including at the same time, a variant of "small basal cells") and reticular acanthotic. Special mention has to be made as well to the activated and pure forms which, though being the result of evolutive accidental phenomena, no doubt they have very particular and distinctive histopathological aspects. Further, other variants are discussed such a clonal and acantholytic seborrheic keratosis, as well as the significance of inverted follicular keratosis and of melanoacanthoma.
为了基于结构形态学和细胞学对脂溢性角化病进行分类，人们对其组织病理学特征进行了研究。所研究的210例脂溢性角化病可分为几种类型，其中我们必须指出最重要的三种：角化过度型、腺样型和棘层肥厚型。最后一种可呈现两种截然不同的图像：均匀性棘层肥厚型（同时包括“小基底细胞”变体）和网状棘层肥厚型。还必须特别提及活化型和单纯型，尽管它们是演变过程中偶然现象的结果，但无疑具有非常特殊和独特的组织病理学特征。此外，还讨论了其他变体，如克隆性和棘层松解性脂溢性角化病，以及毛囊内翻性角化病和黑素棘皮瘤的意义。
