The rationale for using hydroxycarbamide in the treatment of sickle cell disease.
作者信息
Rees David C
出版信息
Haematologica. 2011 Apr;96(4):488-91. doi: 10.3324/haematol.2011.041988.
Abstract
摘要
相似文献
1
The rationale for using hydroxycarbamide in the treatment of sickle cell disease.使用羟基脲治疗镰状细胞病的基本原理。
Haematologica. 2011 Apr;96(4):488-91. doi: 10.3324/haematol.2011.041988.
2
The rationale for using hydroxycarbamide in the treatment of sickle cell disease" (Haematologica 2011;96:488-491). Reply.使用羟基脲治疗镰状细胞病的理论依据”（《血液学》2011年；96:488 - 491）。回复
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Treating sickle cell anaemia with hydroxycarbamide.用羟基脲治疗镰状细胞贫血。
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Hydroxycarbamide use in young children with sickle-cell anaemia.羟基脲在镰状细胞贫血幼儿中的应用。
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Hydroxycarbamide use in young children with sickle-cell anaemia.羟基脲在镰状细胞贫血幼儿中的应用。
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Hydroxycarbamide for sickle-cell anaemia in infancy.羟基脲用于婴儿镰状细胞贫血
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Hydroxyurea therapy decreases coagulation and endothelial activation in sickle cell disease: a Longitudinal Study.羟基脲疗法可降低镰状细胞病患者的凝血和内皮细胞活化：一项纵向研究
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Hydroxyurea marketed for sickle cell anemia.羟基脲用于治疗镰状细胞贫血。
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Hydroxyurea for sickle cell anemia.羟基脲用于镰状细胞贫血。
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Long-term use of hydroxyurea for sickle cell anemia.羟基脲用于镰状细胞贫血的长期治疗。
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本文引用的文献
1
Differential modulation of adhesion molecule expression by hydroxycarbamide in human endothelial cells from the micro- and macrocirculation: potential implications in sickle cell disease vasoocclusive events.羟脲对人微血管和大血管内皮细胞黏附分子表达的差异调节：在镰状细胞病血管阻塞事件中的潜在意义。
Haematologica. 2011 Apr;96(4):534-42. doi: 10.3324/haematol.2010.026740. Epub 2011 Jan 12.
2
Participation of Mac-1, LFA-1 and VLA-4 integrins in the in vitro adhesion of sickle cell disease neutrophils to endothelial layers, and reversal of adhesion by simvastatin.Mac-1、LFA-1 和 VLA-4 整合素在镰状细胞病中性粒细胞与内皮细胞层体外黏附中的作用，以及辛伐他汀逆转黏附的作用。
Haematologica. 2011 Apr;96(4):526-33. doi: 10.3324/haematol.2010.032912. Epub 2010 Dec 20.
3
Sickle-cell disease.镰状细胞病。
Lancet. 2010 Dec 11;376(9757):2018-31. doi: 10.1016/S0140-6736(10)61029-X. Epub 2010 Dec 3.
4
Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model.羟基脲治疗需要诱导胎儿血红蛋白（HbF）产生才能对镰状细胞小鼠模型产生临床获益。
Haematologica. 2010 Sep;95(9):1599-603. doi: 10.3324/haematol.2010.023325. Epub 2010 Apr 7.
5
How I use hydroxyurea to treat young patients with sickle cell anemia.我如何使用羟基脲治疗年轻的镰状细胞贫血患者。
Blood. 2010 Jul 1;115(26):5300-11. doi: 10.1182/blood-2009-04-146852. Epub 2010 Mar 11.
6
The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS).羟基脲长期治疗对镰状细胞综合征成年患者发病率和死亡率的影响：一项 17 年单中心试验（LaSHS）的结果。
Blood. 2010 Mar 25;115(12):2354-63. doi: 10.1182/blood-2009-05-221333. Epub 2009 Nov 10.
7
Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males.镰状细胞病及羟基脲治疗对男性精子参数和生育能力的影响。
Haematologica. 2008 Jul;93(7):988-93. doi: 10.3324/haematol.11515. Epub 2008 May 27.
8
HYDROXYUREA. A NEW TYPE OF POTENTIAL ANTITUMOR AGENT.
J Med Chem. 1963 Mar;6:201. doi: 10.1021/jm00338a026.
9
Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.羟基脲对成年镰状细胞贫血患者死亡率和发病率的影响：长达9年治疗期的风险与益处
JAMA. 2003 Apr 2;289(13):1645-51. doi: 10.1001/jama.289.13.1645.
10
Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase.羟基脲通过一氧化氮依赖的可溶性鸟苷酸环化酶激活来诱导胎儿血红蛋白。
J Clin Invest. 2003 Jan;111(2):231-9. doi: 10.1172/JCI16672.
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