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超声引导下髌下神经阻滞在 ACL 重建术中的应用:一项前瞻性、随机、双盲、安慰剂对照临床试验。

Ultrasound-guided infrapatellar nerve block for anterior cruciate ligament repair: a prospective, randomised, double-blind, placebo-controlled clinical trial.

机构信息

Department of Paediatric Anaesthesia & Intensive Care, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Eur J Anaesthesiol. 2011 Jul;28(7):511-8. doi: 10.1097/EJA.0b013e32834515ba.

DOI:10.1097/EJA.0b013e32834515ba
PMID:21455076
Abstract

BACKGROUND AND OBJECTIVES

We have previously described an ultrasonography-guided technique to block the infrapatellar nerve that is associated with an extended duration of anaesthesia. The aim of the present study was to investigate the clinical usefulness of this new technique in patients undergoing arthroscopy-assisted anterior cruciate ligament repair.

METHODS

Using a prospective, double-blind and placebo-controlled study design, 64 patients were randomised to get an active infrapatellar nerve block (IPNB; 10 ml levobupivacaine 0.5%; n = 31) or a sham block with isotonic saline (n = 33) as a complement to a standardised anaesthetic and analgesic regimen. Pain was recorded hourly and the proportion of patients with a pain intensity of more than 3 (numeric rating scale 0-10) during 12-24 postoperative hours was chosen as the primary end-point of the study. Duration of the block, numbers of hours spent sleeping and other secondary parameters were also recorded.

RESULTS

The proportion of patients with a pain score of higher than 3 at rest was significantly lower in patients receiving an IPNB during postoperative hours 16-24 (P = 0.0117) as well as on muscular activity during postoperative hours 16-24 (P = 0.0039). Median block duration was 23 h (95% confidence interval 19-24 h). A significantly larger proportion of patients were asleep during the time period 13-24 h after surgery in patients given active treatment as compared to sham block (P < 0.0269).

CONCLUSION

Adjunct use of an ultrasound-guided block of the infrapatellar nerve is associated with improved pain relief and an increased number of sleep hours after arthroscopy-assisted anterior cruciate ligament repair.

摘要

背景与目的

我们之前描述了一种超声引导下的技术,可以阻滞髌下神经,从而延长麻醉时间。本研究旨在探讨该新技术在关节镜辅助前交叉韧带修复术中的临床应用价值。

方法

采用前瞻性、双盲、安慰剂对照研究设计,将 64 例患者随机分为主动髌下神经阻滞组(10 ml 左旋布比卡因 0.5%;n = 31)或假阻滞生理盐水组(n = 33),两组均辅以标准化的麻醉和镇痛方案。每小时记录一次疼痛,并将术后 12-24 小时疼痛强度大于 3 分(数字评分量表 0-10)的患者比例作为研究的主要终点。还记录了阻滞持续时间、睡眠时间和其他次要参数。

结果

接受 IPNB 的患者在术后 16-24 小时(P = 0.0117)和术后 16-24 小时肌肉活动时(P = 0.0039)静息时疼痛评分高于 3 分的患者比例明显更低。阻滞持续时间中位数为 23 小时(95%置信区间 19-24 小时)。与假阻滞相比,接受主动治疗的患者在术后 13-24 小时期间入睡的比例明显更高(P < 0.0269)。

结论

关节镜辅助前交叉韧带修复术后,超声引导下髌下神经阻滞辅助应用可减轻疼痛,增加睡眠时间。

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