Garavelli P L, Azzini M
Divisione di Malattie Infettive, Ospedale Civile, Alessandria.
Minerva Med. 1990 Jul-Aug;81(7-8 Suppl):115-6.
Carbamazepine (CBZ) can produce serious side-effects such as hepatitis, LES, agranulocytosis, aplastic anaemia and skin eruptions. The latter, of polymorphous appearance (morbilliform, orticorioid and vesicular) depend on the levels of CBZ and retreat rapidly with the administration of prednisone. 2 cases of rash following introduction of the drug quickly resolved with its suspension are reported.
卡马西平(CBZ)可产生严重的副作用,如肝炎、狼疮样综合征、粒细胞缺乏症、再生障碍性贫血和皮疹。皮疹形态多样(麻疹样、荨麻疹样和水疱样),取决于卡马西平的血药浓度,给予泼尼松后皮疹迅速消退。本文报告了2例在开始使用该药物后出现皮疹的病例,在停药后皮疹迅速消退。