J Biomed Opt. 2011 Mar;16(3):030503. doi: 10.1117/1.3553005.
Quantitative measurements of scattering properties are invaluable for optical techniques in medicine. However, noninvasive, quantitative measurements of scattering properties over a large wavelength range remain challenging. We introduce low-coherence spectroscopy as a noninvasive method to locally and simultaneously measure scattering μ(s) and backscattering μ(b) coefficients from 480 to 700 nm with 8 nm spectral resolution. The method is tested on media with varying scattering properties (μ(s) = 1 to 34 mm(-1) and μ(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory.
定量测量散射特性对于医学中的光学技术非常重要。然而，在大波长范围内进行非侵入式、定量测量散射特性仍然具有挑战性。我们引入低相干光谱学作为一种非侵入式方法，可在 480 至 700nm 的波长范围内以 8nm 的光谱分辨率，对散射 μ(s) 和反向散射 μ(b) 系数进行局部和同时测量。该方法在具有不同散射特性的介质（μ(s) = 1 至 34mm(-1)和 μ(b) = 2.10(-6) 至 2.10(-3)mm(-1))上进行了测试，其中包含不同尺寸的聚苯乙烯球。结果与 Mie 理论非常吻合。
