Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P.O. Box 22700,NL-1100 DE Amsterdam, The Netherlands.
Opt Lett. 2009 Dec 1;34(23):3746-8. doi: 10.1364/OL.34.003746.
Low-coherence spectroscopy (LCS) is a spectroscopic method that allows for quantitative and localized assessment of absorption spectra by combining reflection spectroscopy with low-coherence interferometry. We describe absorption coefficient (mu(a)) measurements by LCS in tissue simulating phantoms with varying scattering and absorbing properties. We used LCS in the 455-680 nm wavelength range with a spectral resolution of 8 nm to obtain mu(a) spectra with +/-0.5 mm(-1) accuracy. We conclude that LCS is a promising technique for the in vivo determination of tissue chromophore concentrations.
低相干光谱学（LCS）是一种光谱方法，通过将反射光谱学与低相干干涉测量相结合，实现吸收光谱的定量和局部评估。我们描述了在具有不同散射和吸收特性的组织模拟体模中通过 LCS 进行吸收系数（μ(a)）测量。我们使用 LCS 在 455-680nm 波长范围内，光谱分辨率为 8nm，以获得精度为 +/-0.5mm(-1)的 μ(a)光谱。我们得出结论，LCS 是一种很有前途的技术，可用于体内确定组织色团浓度。
