D'Or Institute for Research and Education, Rua Diniz Cordeiro, 30, Botafogo, Rio de Janeiro 22281-100, Brazil.
Crit Care. 2011;15(2):137. doi: 10.1186/cc10099. Epub 2011 Mar 24.
Severe community-acquired pneumonia is a major cause of admission to intensive care units and its mortality rates remain exceedingly high. In the search for adjunctive therapies, clinicians who were encouraged by available, though limited, evidence prescribed steroids in most patients with severe sepsis or septic shock, including those with community-acquired pneumonia. Current evidence demonstrates that, whereas corticosteroids should not be routinely employed as adjuvant therapy for severe community-acquired pneumonia, there is sufficient equipoise to continue studying the use of corticosteroids.
严重社区获得性肺炎是入住重症监护病房的主要原因,其死亡率仍然极高。在寻找辅助治疗方法的过程中,临床医生根据现有但有限的证据,对大多数严重脓毒症或感染性休克患者(包括社区获得性肺炎患者)开了类固醇。目前的证据表明,虽然皮质类固醇不应常规用于严重社区获得性肺炎的辅助治疗,但仍有足够的均衡性继续研究皮质类固醇的使用。