Institute of Biotechnology and Genetic Engineering, KPK Agricultural University, Peshawar, Pakistan.
Virol J. 2011 Apr 1;8:154. doi: 10.1186/1743-422X-8-154.
Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 224 (3.13%) were positive for anti-HCV antibodies by ICT, 135 (1.89%) by ELISA while 118 (1.65%) blood donors had active HCV infection as detected by RT-PCR. We suggest that ELISA should be used for anti-HCV screening in public sector hospitals and health care units.
丙型肝炎是一种由丙型肝炎病毒引起的致命肝脏疾病。在这项研究中，来自巴基斯坦开伯尔-普赫图赫瓦省和联邦直辖部落地区（FATA）不同地区的献血者通过 ICT（免疫层析试验）、ELISA 和 RT-PCR 检测抗 HCV 抗体和 HCV RNA。在 7148 名献血者中，224 名（3.13%）通过 ICT、135 名（1.89%）通过 ELISA 检测抗 HCV 抗体阳性，118 名（1.65%）献血者通过 RT-PCR 检测到 HCV 感染呈阳性。我们建议在公立医院和医疗机构使用 ELISA 进行抗 HCV 筛查。
