Department of Craniofacial Orthodontics, Chang Gung Memorial Hospital, Taipei, Taiwan.
Int J Oral Maxillofac Surg. 2011 Jul;40(7):672-8. doi: 10.1016/j.ijom.2011.02.021. Epub 2011 Apr 1.
Median facial dysplasia affects a subset of patients with cleft lip and palate exhibiting certain characteristics of median facial structure deficiencies without definable gross abnormalities of the brain. The aim of this study was to describe the craniofacial and dental morphology of almost skeletally mature patients with median facial dysplasia. Patients were selected for this retrospective study if they were diagnosed with median facial dysplasia and ≥15 years old. The craniofacial and dental morphology was evaluated by analysing cephalometric and panoramic radiographs. This sample of median facial dysplasia patients (9 males and 11 females; 6 unilateral and 14 bilateral clefts) had a mean age of 16.7 ± 1.9 years. Controls were age-, sex-, cleft type-matched, and nonsyndromic patients. The results showed that in patients with median facial dysplasia, the anterior cranial base and midface were shorter than in controls. The median facial dysplasia inter-orbital distance was shorter and the nasal bone was more retrusive than in controls. All patients with median facial dysplasia had several missing permanent teeth. These features require extensive surgical, orthodontic, and dental rehabilitation procedures.
中位面部发育不良影响了一小部分唇腭裂患者，这些患者表现出某些中面部结构缺陷的特征，而大脑没有明显的异常。本研究的目的是描述近骨骼成熟的中位面部发育不良患者的颅面和牙齿形态。如果患者被诊断为中位面部发育不良且年龄≥15 岁，则选择这些中位面部发育不良患者进行回顾性研究。通过分析头颅侧位片和全景片评估颅面和牙齿形态。该中位面部发育不良患者样本（9 名男性和 11 名女性；6 例单侧和 14 例双侧裂隙）的平均年龄为 16.7±1.9 岁。对照组为年龄、性别、裂隙类型匹配的非综合征患者。结果表明，中位面部发育不良患者的前颅底和中面部比对照组更短。中位面部发育不良患者的眶间距离更短，鼻骨更后缩。所有中位面部发育不良患者都有几颗恒牙缺失。这些特征需要广泛的手术、正畸和牙科修复程序。
