Kaiser Permanente Center for Health Research, Portland, OR 97227, USA.
Psychiatr Serv. 2011 Apr;62(4):367-73. doi: 10.1176/ps.62.4.pss6204_0367.
The aim of this study was to replicate and extend results of a previous blended efficacy and effectiveness trial of a low-intensity, manual-based guided self-help form of cognitive-behavioral therapy (CBT-GSH) for the treatment of binge eating disorders in a large health maintenance organization (HMO) and to compare them with usual care.
To extend previous findings, the investigators modified earlier recruitment and assessment approaches and conducted a randomized clinical trial to better reflect procedures that may be reasonably carried out in real-world practices. The intervention was delivered by master's-level interventionists to 160 female members of a health maintenance organization who met diagnostic criteria for recurrent binge eating. Data collected at baseline, immediately posttreatment, and at six- and 12-month follow-ups were used in intent-to-treat analyses.
At the 12-month follow-up, CBT-GSH resulted in greater remission from binge eating (35%, N=26) than usual care (14%, N=10) (number needed to treat=5). The CBT-GSH group also demonstrated greater improvements in dietary restraint (d=.71) and eating, shape, and weight concerns (d=1.10, 1.24, and .98, respectively) but not weight change.
Replication of the pattern of previous findings suggests that CBT-GSH is a robust treatment for patients with recurrent binge eating. The magnitude of changes was significantly smaller than in the original study, however, suggesting that patients recruited and assessed with less intensive procedures may respond differently from their counterparts enrolled in trials requiring more comprehensive procedures.
本研究旨在复制和扩展之前一项低强度、基于手册的认知行为疗法自助形式(CBT-GSH)治疗暴食障碍的混合疗效和有效性试验的结果,该试验在一家大型健康维护组织(HMO)中进行,并将其与常规护理进行比较。
为了扩展先前的发现,研究人员修改了早期的招募和评估方法,并进行了一项随机临床试验,以更好地反映在实际实践中可能合理进行的程序。干预措施由硕士水平的干预者提供给符合复发性暴食诊断标准的 160 名健康维护组织女性成员。在基线、治疗后即刻以及 6 个月和 12 个月随访时收集的数据用于意向治疗分析。
在 12 个月的随访中,CBT-GSH 导致更多的暴食症缓解(35%,N=26),而常规护理为 14%(N=10)(需要治疗的人数=5)。CBT-GSH 组在饮食控制(d=.71)和饮食、体型和体重担忧(d=1.10、1.24 和.98)方面也表现出更大的改善,但体重没有变化。
先前研究结果模式的复制表明,CBT-GSH 是治疗复发性暴食症患者的有效治疗方法。然而,变化的幅度明显小于原始研究,这表明使用不那么密集的程序招募和评估的患者可能与需要更全面程序的试验中招募的患者反应不同。