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胰岛素在调节大鼠组织中腺苷脱氨酶活性中的作用

On the role of insulin in regulation of adenosine deaminase activity in rat tissues.

作者信息

Rutkiewicz J, Górski J

机构信息

Department of Physiology, Medical School, Białystok, Poland.

出版信息

FEBS Lett. 1990 Oct 1;271(1-2):79-80. doi: 10.1016/0014-5793(90)80376-t.

DOI:10.1016/0014-5793(90)80376-t
PMID:2146155
Abstract

After administration of insulin adenosine deaminase activity was reduced in different skeletal muscle types, the heart and the liver. On the other hand profound reduction in the plasma insulin concentration (streptozotocin diabetes) resulted in elevation of the enzyme activity in the tissues. It is concluded that the local concentration of adenosine may be effected by the concentration of insulin in the plasma.

摘要

注射胰岛素后,不同类型的骨骼肌、心脏和肝脏中的腺苷脱氨酶活性降低。另一方面,血浆胰岛素浓度大幅降低(链脲佐菌素诱导的糖尿病)会导致组织中该酶活性升高。由此得出结论,血浆中胰岛素的浓度可能会影响局部腺苷的浓度。

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