Varsano R, Matringe M, Magnin N, Mornet R, Scalla R
Laboratoire des Herbicides, INRA, Dijon, France.
FEBS Lett. 1990 Oct 15;272(1-2):106-8. doi: 10.1016/0014-5793(90)80459-v.
The specific binding of the herbicide acifluorfen 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid to corn etioplast membranes is competitively inhibited by protoporphyrinogen IX, the substrate of protoporphyrinogen oxidase. Three other peroxidizing molecules, oxadiazon [5-terbutyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol -2-one], LS 82556 [(S)3-N-(methylbenzyl)carbamoyl-5-propionyl-2,6-lutidine], and M&B 39279 [5-amino-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazol], also compete with acifluorfen for its binding site. The four herbicides thus bind to the same site, or to closely located sites, on the enzyme protoporphyrinogen oxidase.
除草剂三氟羧草醚（5-[2-氯-4-(三氟甲基)苯氧基]-2-硝基苯甲酸）与玉米黄化质体膜的特异性结合受到原卟啉原氧化酶底物原卟啉原IX的竞争性抑制。另外三种过氧化分子，恶草酮（5-叔丁基-3-(2,4-二氯-5-异丙氧基苯基)-1,3,4-恶二唑-2-酮）、LS 82556（(S)3-N-(甲基苄基)氨基甲酰基-5-丙酰基-2,6-二甲基吡啶）和M&B 39279（5-氨基-4-氰基-1-(2,6-二氯-4-三氟甲基苯基)吡唑），也与三氟羧草醚竞争其结合位点。因此，这四种除草剂都与原卟啉原氧化酶上的同一位点或紧密相邻的位点结合。
