基于公共子串长度分布的蛋白质序列系统发育分析。
Phylogenetic analysis of protein sequences based on distribution of length about common sub-string.
机构信息
School of Mathematical Sciences, Dalian University of Technology, 116024 Dalian, People's Republic of China.
出版信息
Protein J. 2011 Mar;30(3):167-72. doi: 10.1007/s10930-011-9318-0.
Abstract
Up to now, various approaches for phylogenetic analysis have been developed. Almost all of them put stress on analyzing nucleic acid sequences or protein primary sequences. In this paper, we propose a new sequence distance for efficient reconstruction of phylogenetic trees based on the distribution of length about common sub-sequences between two sequences. We describe some applications of this method, which not only show the validity of the method, but also suggest a number of novel phylogenetic insights.
摘要
到目前为止，已经开发了多种用于系统发育分析的方法。几乎所有方法都侧重于分析核酸序列或蛋白质一级序列。在本文中，我们基于两个序列之间公共子序列长度的分布，提出了一种新的序列距离，用于有效地重建系统发育树。我们描述了这种方法的一些应用，这些应用不仅表明了该方法的有效性，而且还提供了一些新的系统发育见解。
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