Renal handling of phosphate in vivo and in vitro by the X-linked hypophosphatemic male mouse: evidence for a defect in the brush border membrane.

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作者信息

Tenenhouse H S, Scriver C R, McInnes R R, Glorieux F H

出版信息

Kidney Int. 1978 Sep;14(3):236-44. doi: 10.1038/ki.1978.115.

DOI:10.1038/ki.1978.115

PMID:214620

Abstract

摘要

相似文献

Renal handling of phosphate in vivo and in vitro by the X-linked hypophosphatemic male mouse: evidence for a defect in the brush border membrane.

Kidney Int. 1978 Sep;14(3):236-44. doi: 10.1038/ki.1978.115.

The defect in transcellular transport of phosphate in the nephron is located in brush-border membranes in X-linked hypophosphatemia (Hyp mouse model).在X连锁低磷血症（Hyp小鼠模型）中，肾单位中磷酸盐跨细胞转运的缺陷位于刷状缘膜。

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Renal adaptation to phosphate deprivation in the Hyp mouse with X-linked hypophosphatemia.

Can J Biochem. 1979 Jun;57(6):938-44. doi: 10.1139/o79-114.

Transport of phosphate by plasma membranes of the jejunum and kidney of the mouse model of hypophosphatemic vitamin D-resistant rickets.低磷性维生素D抵抗性佝偻病小鼠模型空肠和肾脏质膜对磷酸盐的转运

Proc Soc Exp Biol Med. 1993 Jul;203(3):328-35. doi: 10.3181/00379727-203-43607.

Phosphate transport across renal cortical brush border membrane vesicles from rats stabilized on a normal, high or low phosphate diet.磷酸盐在正常、高磷或低磷饮食条件下稳定饲养的大鼠肾皮质刷状缘膜囊泡中的转运。

Life Sci. 1979 Mar 5;24(10):881-7. doi: 10.1016/0024-3205(79)90337-0.

The renal phosphate transport defect in normal mice parabiosed to X-linked hypophosphatemic mice persists after parathyroidectomy.与X连锁低磷血症小鼠联体共生的正常小鼠的肾磷酸盐转运缺陷在甲状旁腺切除术后持续存在。

J Bone Miner Res. 1989 Aug;4(4):523-32. doi: 10.1002/jbmr.5650040411.

Renal phosphate transport and vitamin D metabolism in X-linked hypophosphatemic Gy mice: responses to phosphate deprivation.X连锁低磷血症Gy小鼠的肾磷酸盐转运与维生素D代谢：对磷酸盐缺乏的反应

Endocrinology. 1992 Jul;131(1):51-6. doi: 10.1210/endo.131.1.1612032.

Thyroid hormones increase renal brush border membrane transport of phosphate in X-linked hypophosphatemic (Hyp) mice.甲状腺激素可增加X连锁低磷血症（Hyp）小鼠肾脏刷状缘膜对磷酸盐的转运。

Endocrinology. 1985 Aug;117(2):613-9. doi: 10.1210/endo-117-2-613.

The effects of Mendelian mutation on renal sulfate and phosphate transport in man and mouse.孟德尔突变对人和小鼠肾脏硫酸盐及磷酸盐转运的影响。

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Effect of the Hyp mutation and diet-induced hyperparathyroidism on renal parathyroid hormone- and forskolin-stimulated adenosine 3',5'-monophosphate production and brush border membrane phosphate transport.Hyp 突变和饮食诱导的甲状旁腺功能亢进对肾中甲状旁腺激素和福斯可林刺激的 3',5'-环磷酸腺苷生成及刷状缘膜磷酸盐转运的影响。

Endocrinology. 1986 Mar;118(3):1047-53. doi: 10.1210/endo-118-3-1047.

引用本文的文献

Renal expression of Na+-phosphate cotransporter mRNA and protein: effect of the Gy mutation and low phosphate diet.钠-磷酸盐共转运体mRNA和蛋白在肾脏中的表达：Gy突变和低磷饮食的影响

Pflugers Arch. 1996 Apr;431(6):936-41. doi: 10.1007/s004240050088.

The gene for X-linked hypophosphataemic rickets maps to a 200-300kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE).X连锁低磷血症性佝偻病基因定位于Xp22.1的一个200 - 300kb区域，且位于一个含有假定维生素D反应元件（VDRE）的单个酵母人工染色体上。

Hum Genet. 1996 Mar;97(3):345-52. doi: 10.1007/BF02185769.

Renal adaptation to phosphate deprivation: lessons from the X-linked Hyp mouse.肾脏对磷缺乏的适应性：来自X连锁低磷血症小鼠的启示。

Pediatr Nephrol. 1993 Jun;7(3):312-8. doi: 10.1007/BF00853232.

Renal Na(+)-phosphate cotransport in murine X-linked hypophosphatemic rickets. Molecular characterization.小鼠X连锁低磷血症性佝偻病中的肾钠-磷协同转运。分子特征

J Clin Invest. 1994 Feb;93(2):671-6. doi: 10.1172/JCI117019.

New markers for linkage analysis of X-linked hypophosphataemic rickets.X连锁低磷性佝偻病连锁分析的新标记物。

Hum Genet. 1993 Jul;91(6):571-5. doi: 10.1007/BF00205082.

Chromosomal localization of the human renal sodium phosphate transporter to chromosome 5: implications for X-linked hypophosphatemia.人类肾钠磷转运体在5号染色体上的定位：对X连锁低磷血症的意义。

Pediatr Res. 1994 Apr;35(4 Pt 1):510-3.

Molecular biology of hypophosphataemic rickets and oncogenic osteomalacia.低磷性佝偻病和肿瘤性骨软化症的分子生物学

Hum Genet. 1994 Nov;94(5):457-67. doi: 10.1007/BF00211008.

Alkaline phosphatase activity does not mediate phosphate transport in the renal-cortical brush-border membrane.碱性磷酸酶活性不介导肾皮质刷状缘膜中的磷酸盐转运。

Biochem J. 1980 Aug 15;190(2):473-6. doi: 10.1042/bj1900473.

It's not just how low you make it, but how you make it low.关键不在于你把它降得有多低，而在于你是如何把它降下来的。

West J Med. 1981 Jan;134(1):56-7.

Inherited metabolic disease in laboratory animals: a review.实验动物中的遗传性代谢疾病：综述

J Inherit Metab Dis. 1980;3(4):133-43. doi: 10.1007/BF02312547.

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