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经皮冠状动脉旋磨术

Percutaneous coronary rotary ablation.

作者信息

Bertrand M E, Lablanche J M, Fourrier J L, Bauters C, Leroy F

机构信息

Division of Cardiology, University Hospital, Lille, France.

出版信息

Herz. 1990 Oct;15(5):285-91.

PMID:2146203
Abstract

The rotablator is a high-speed rotating ablative system developed to grind obstructing atheromatous material into fine particles. It consists of a rotating burr attached to a long, flexible driving shaft with a central flexible guidewire. The device rotates with a speed of 190,000 r.p.m. In this study, after appropriate pretreatment, the atherectomy system was positioned over the guidewire, the steerable guidewire advanced to beyond the stenosis, the abrasive burr positioned at the stenosis and the rotation commenced. The abrasive burr was advanced until a resistance was experienced and then, with back and forth motion, further advanced until passage of the stenosis was achieved. The procedure was repeated six to eight times until no further mechanical resistance was encountered. Patients were maintained on aspirin and nifedipine. With a burr size between 1.5 and 2 mm, in 32 patients in the right coronary artery, twelve patients in the left anterior descending artery and eight patients in the circumflex artery, an average increase in diameter from 0.52 +/- 0.28 mm to 1.27 +/- 0.37 mm was achieved with respective reduction in the stenosis from 80 +/- 11% to 47 +/- 17%. Balloon dilatation was subsequently carried out in 19 patients in 15 of whom residual significant stenosis was due to the use of an inadequately large burr. There were no deaths. During ablation, in six patients evanescent (of few seconds in duration), spontaneously-reversible AV-block developed probably due to embolization of particles into the sinus node artery. Two patients developed coronary spasm, three had acute occlusion with subsequent myocardial infarction.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

旋磨仪是一种高速旋转的消融系统,旨在将阻塞性动脉粥样硬化物质研磨成细颗粒。它由一个连接在长而灵活的驱动轴上的旋转磨头和一根中央柔性导丝组成。该设备以每分钟190,000转的速度旋转。在本研究中,经过适当的预处理后,将旋切系统置于导丝上方,将可操纵的导丝推进至狭窄段远端,将磨蚀性磨头置于狭窄处并开始旋转。磨蚀性磨头向前推进,直到感觉到阻力,然后通过前后移动进一步推进,直到通过狭窄段。该过程重复6至8次,直到不再遇到机械阻力。患者持续服用阿司匹林和硝苯地平。使用1.5至2毫米的磨头,在右冠状动脉的32例患者、左前降支动脉的12例患者和回旋支动脉的8例患者中,平均直径从0.52±0.28毫米增加到1.27±0.37毫米,相应地狭窄率从80±11%降低到47±17%。随后对19例患者进行了球囊扩张,其中15例患者残留明显狭窄是由于使用的磨头尺寸不足。无死亡病例。在消融过程中,6例患者出现短暂性(持续数秒)、自发可逆的房室传导阻滞,可能是由于颗粒栓塞至窦房结动脉所致。2例患者发生冠状动脉痉挛,3例患者出现急性闭塞并随后发生心肌梗死。(摘要截选至250字)

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