野葛花中的异黄酮苷

Isoflavonoid glycosides from the flowers of Pueraria lobata.

作者信息

Yu Ying-Lu, Liao Yi-Ting, Li Xian, Ye Yang, Ke Chang-Qiang, Li Xi-Qiang, Yang Xin-Zhou, Yao Mei-Cun

机构信息

Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang, China.

出版信息

J Asian Nat Prod Res. 2011 Apr;13(4):284-9. doi: 10.1080/10286020.2011.554404.

DOI:10.1080/10286020.2011.554404

PMID:21462030

Abstract

Pueraria lobata flower is a medicinal herb for treating intoxication, hepatic, and gastrointestinal tract lesions induced by alcohol. This study aims to investigate the isoflavonoid glycosides in P. lobata flowers. Two new isoflavone compounds were isolated from the extract of P. lobata flowers. Their structures were determined to be 5,6,7,4'-tetrahydroxyisoflavone-6,7-di-O-β-D-glucopyranoside and 5,6,7-trihydroxy-4'-methoxyisoflavone-6,7-di-O-β-D-glucopyranoside on the basis of spectroscopic means including HR-ESI-MS, UV, IR, ¹H, and ¹³C NMR.

摘要

葛花是一种用于治疗酒精引起的中毒、肝脏和胃肠道损伤的草药。本研究旨在研究葛花中的异黄酮苷。从葛花提取物中分离出两种新的异黄酮化合物。基于高分辨电喷雾电离质谱（HR-ESI-MS）、紫外光谱（UV）、红外光谱（IR）、氢核磁共振（¹H NMR）和碳核磁共振（¹³C NMR）等光谱手段，确定它们的结构分别为5,6,7,4'-四羟基异黄酮-6,7-二-O-β-D-吡喃葡萄糖苷和5,6,7-三羟基-4'-甲氧基异黄酮-6,7-二-O-β-D-吡喃葡萄糖苷。