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使用诺雷德对晚期前列腺癌进行二线治疗。

Secondary treatment of advanced cancer of the prostate with Zoladex.

作者信息

Klarskov P, Lund F, Petersen S E

机构信息

Department of Urology, Herlev Hospital, Denmark.

出版信息

Int Urol Nephrol. 1990;22(4):359-62. doi: 10.1007/BF02549796.

DOI:10.1007/BF02549796
PMID:2146234
Abstract

Twelve patients with advanced prostatic carcinoma and relapse following previous hormone manipulation therapy were treated with Zoladex-depot every 4 weeks. The treatment was well tolerated and the endocrine response was satisfactory. However, no clinically important improvement was obtained.

摘要

12例晚期前列腺癌患者,在先前接受激素治疗后复发,每4周接受一次长效醋酸戈舍瑞林治疗。治疗耐受性良好,内分泌反应令人满意。然而,未获得临床上重要的改善。

相似文献

1
Secondary treatment of advanced cancer of the prostate with Zoladex.使用诺雷德对晚期前列腺癌进行二线治疗。
Int Urol Nephrol. 1990;22(4):359-62. doi: 10.1007/BF02549796.
2
Zoladex treatment of symptomatic prostatic carcinoma.戈舍瑞林治疗有症状的前列腺癌。
Am J Clin Oncol. 1988;11 Suppl 2:S123-6. doi: 10.1097/00000421-198801102-00031.
3
LH-RH agonist, Zoladex (Goserelin), depot formulation in the treatment of prostatic cancer. Randomized dose-finding trial in Japan.促黄体生成素释放激素激动剂,诺雷德(戈舍瑞林)长效剂型治疗前列腺癌。日本随机剂量探索试验。
Am J Clin Oncol. 1988;11 Suppl 2:S108-11. doi: 10.1097/00000421-198801102-00026.
4
Long term therapy with a depot LHRH analogue (Zoladex) in patients with advanced prostatic cancer.长效促性腺激素释放激素类似物(诺雷德)对晚期前列腺癌患者的长期治疗。
Prog Clin Biol Res. 1987;243A:221-7.
5
Treatment of metastatic prostate carcinoma with the depot LRH analog Zoladex.用长效促性腺激素释放激素类似物戈舍瑞林治疗转移性前列腺癌。
Prostate. 1988;12(2):119-27. doi: 10.1002/pros.2990120203.
6
Clinical study of an LH-RH agonist (ICI 118.630, Zoladex) in the treatment of prostatic cancer.一种促黄体生成素释放激素激动剂(ICI 118.630,戈舍瑞林)治疗前列腺癌的临床研究。
Am J Clin Oncol. 1988;11 Suppl 2:S117-9. doi: 10.1097/00000421-198801102-00029.
7
Interim report of a randomized trial comparing Zoladex 3.6 mg depot with diethylstilbestrol 3 mg/day in advanced prostate cancer. The West Midlands Urology Research Group.一项比较3.6毫克戈舍瑞林长效注射剂与每日3毫克己烯雌酚治疗晚期前列腺癌的随机试验中期报告。西米德兰兹泌尿外科研究小组。
Am J Clin Oncol. 1988;11 Suppl 2:S173-5. doi: 10.1097/00000421-198801102-00040.
8
Treatment of advanced prostatic carcinoma with a slow release depot LHRH analogue (Zoladex depot).使用缓释长效促性腺激素释放激素类似物(诺雷德长效注射剂)治疗晚期前列腺癌。
Scand J Urol Nephrol Suppl. 1988;110:109-12.
9
Zoladex: a sustained-release, monthly luteinizing hormone-releasing hormone analogue for the treatment of advanced prostate cancer.诺雷德:一种用于治疗晚期前列腺癌的长效、每月一次的促黄体生成素释放激素类似物。
J Clin Oncol. 1987 Jun;5(6):912-7. doi: 10.1200/JCO.1987.5.6.912.
10
A new longer-acting LHRH analog depot: preliminary results of a Dutch open phase II clinical study on a 10.8 mg Zoladex 3-monthly depot.一种新型长效促黄体生成激素释放激素(LHRH)类似物长效注射剂:一项关于每三个月注射一次10.8毫克戈舍瑞林长效注射剂的荷兰开放性II期临床研究的初步结果
Eur Urol. 1990;18 Suppl 3:22-5. doi: 10.1159/000463974.

引用本文的文献

1
Goserelin. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in prostate cancer.戈舍瑞林。其药效学和药代动力学特性以及在前列腺癌治疗中的疗效综述。
Drugs Aging. 1995 Apr;6(4):324-43. doi: 10.2165/00002512-199506040-00007.

本文引用的文献

1
Experience with an LHRH analogue in the management of relapsed progressive prostatic cancer.促性腺激素释放激素类似物治疗复发性进展性前列腺癌的经验
Br J Urol. 1984 Oct;56(5):495-8.
2
Treatment of patients with advanced cancer of the prostate using a slow-release (depot) formulation of the LHRH agonist ICI 118630 (Zoladex).使用促黄体生成激素释放激素(LHRH)激动剂ICI 118630(诺雷德)的缓释(长效)制剂治疗晚期前列腺癌患者。
J Endocrinol. 1984 Nov;103(2):R1-4. doi: 10.1677/joe.0.103r001.
3
Advanced carcinoma of the prostate: treatment with a gonadotrophin releasing hormone agonist.
晚期前列腺癌:用促性腺激素释放激素激动剂治疗
Br Med J (Clin Res Ed). 1983 May 21;286(6378):1607-9. doi: 10.1136/bmj.286.6378.1607.
4
The treatment of metastatic prostatic cancer with the slow release LH-RH analogue Zoladex ICI 118630.用缓释促黄体生成素释放激素类似物(Zoladex ICI 118630)治疗转移性前列腺癌。
Br J Urol. 1987 May;59(5):436-42. doi: 10.1111/j.1464-410x.1987.tb04842.x.
5
LHRH analogue as a depot preparation (Zoladex) in the treatment of advanced carcinoma of the prostate followed by orchiectomy as a second line therapy--a phase II study.促黄体生成素释放激素类似物作为长效制剂(诺雷德)用于治疗晚期前列腺癌,随后行睾丸切除术作为二线治疗——一项II期研究。
Scand J Urol Nephrol. 1989;23(3):177-83. doi: 10.3109/00365598909180838.