Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), Research Institute MOVE, University of Amsterdam.
J Oral Rehabil. 2011 Sep;38(9):643-7. doi: 10.1111/j.1365-2842.2011.02221.x. Epub 2011 Apr 5.
It has recently been suggested that wearing a maxillary occlusal splint (i.e. a hard acrylic resin dental appliance that covers the occlusal surfaces of the maxillary dentition and that is being indicated for the treatment of, e.g. temporomandibular pain) may be associated with a risk of aggravating obstructive sleep apnoea (OSA). The present study tested the hypothesis that raising the bite without mandibular protrusion in OSA patients is associated with an increase in the apnoea-hypopnoea index (AHI). Eighteen OSA patients (13 men; 49·5 ± 8·1 years old) received a mandibular advancement device in 0% protrusion of the mandible (0%MAD). The MAD caused a bite rise of 6 mm as measured interincisally. Polysomnographic recordings were obtained at baseline and with the 0%MAD in situ. No statistically significant difference in AHI was noted between the baseline night and the 0%MAD night. However, nine patients had an aggravation in AHI during the night they used the 0%MAD. Taking into account the previously established smallest detectable difference of 12·8 in AHI, the AHI increased in only two of the patients. The outcomes of this study suggest that an increased jaw gape without mandibular protrusion might be associated with a risk of aggravation of OSA for some, but not for all OSA patients. Dental practitioners should be aware of this possible association when treating patients with oral devices that raise the bite.
最近有人提出,佩戴上颌咬合夹板(即覆盖上颌牙列咬合面的硬丙烯酸树脂牙科器具,用于治疗颞下颌疼痛等)可能与加重阻塞性睡眠呼吸暂停(OSA)的风险有关。本研究检验了这样一个假设,即在 OSA 患者中不进行下颌前伸而抬高咬合会导致呼吸暂停低通气指数(AHI)增加。18 名 OSA 患者(13 名男性;49.5±8.1 岁)接受了下颌前伸装置,下颌无前伸(0%MAD)。MAD 导致上下切牙间咬合升高 6mm。在基线和 0%MAD 在位时进行多导睡眠图记录。AHI 在基线夜和 0%MAD 夜之间无统计学差异。然而,有 9 名患者在使用 0%MAD 的夜间 AHI 加重。考虑到之前确定的 AHI 最小可检测差异为 12.8,只有两名患者的 AHI 增加。本研究的结果表明,对于一些 OSA 患者,而非所有 OSA 患者,无下颌前伸的颌间隙增加可能与 OSA 加重的风险相关。当治疗使用抬高咬合的口腔装置的患者时,牙医应注意到这种可能的关联。