Kaymak Oktay, Iskender Can T, Ustunyurt Emin, Yildiz Yasemin, Doganay Melike, Danisman Nuri
Division of Gynecology, Zekai Tahir Burak Women's Hospital, Ankara, Turkey.
J Obstet Gynaecol Res. 2011 Aug;37(8):986-91. doi: 10.1111/j.1447-0756.2010.01469.x. Epub 2011 Apr 4.
To assess maternal and perinatal complications associated with mild gestational hyperglycemia (MGH).
This retrospective study was conducted in the perinatology division of Zekai Tahir Burak Women's Hospital between January and June 2009. Four hundred and eighty one patients with MGH and 212 patients with pre-gestational diabetes or gestational diabetes mellitus (GDM) were recruited in the study. The control group consisted of 479 patients with normal glucose challenge test. Patients with MGH and the control group were compared in terms of maternal and neonatal complications.
The rates of large-for-gestational-age (LGA) or macrosomic infants, pregnancy induced hypertension, primary cesarean delivery, preterm delivery and neonatal hypoglycemia were significantly higher in patients with MGH, GDM or preexisting diabetes. The rates of spontaneous preterm labor, shoulder dystocia, hyperbilirubinemia, low 1-min Apgar score, fetal malformations and neonatal morbidity did not differ between the groups.
MGH is associated with an increased risk of primary cesarean delivery, preterm delivery, pregnancy induced hypertension, and macrosomic and LGA infants.
评估与轻度妊娠期高血糖(MGH)相关的孕产妇及围产期并发症。
本回顾性研究于2009年1月至6月在Zekai Tahir Burak妇女医院围产医学科进行。研究纳入了481例轻度妊娠期高血糖患者以及212例孕前糖尿病或妊娠期糖尿病(GDM)患者。对照组由479例葡萄糖耐量试验正常的患者组成。比较了轻度妊娠期高血糖患者与对照组在孕产妇及新生儿并发症方面的情况。
轻度妊娠期高血糖、妊娠期糖尿病或孕前糖尿病患者中,大于胎龄儿(LGA)或巨大儿、妊娠高血压、初次剖宫产、早产及新生儿低血糖的发生率显著更高。各组间自然早产、肩难产、高胆红素血症、1分钟阿氏评分低、胎儿畸形及新生儿发病率无差异。
轻度妊娠期高血糖与初次剖宫产、早产、妊娠高血压以及巨大儿和大于胎龄儿的风险增加相关。