Department of Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Songpa-gu, Seoul, Korea.
J Thorac Cardiovasc Surg. 2011 Dec;142(6):1464-8. doi: 10.1016/j.jtcvs.2011.03.003. Epub 2011 Apr 3.
To maximize the use of left internal thoracic artery in coronary artery bypass grafting, we have adopted a strategy to revascularize the left anterior descending artery area using a single skeletonized left internal thoracic artery; auto-Y composite grafting and sequential bypassing. This study evaluated graft patency and clinical outcomes after these procedures.
Between 2003 and 2009, 144 patients (112 men; age, 62.9 ± 8.9 years) underwent coronary artery bypass grafting using a single left internal thoracic artery graft to bypass the left anterior descending artery and a diagonal branch. Of them, 57 patients underwent sequential anastomosis (sequential group), and 87 underwent auto-Y composite anastomosis (auto-Y group). Graft patency was assessed using serial multidetector computed tomography.
There were no early mortalities. During a mean follow-up duration of 66.2 ± 44.5 months, there were 8 deaths, including 2 cardiac deaths, and no cases of reintervention. The 2 groups were at similar risks of death on crude and adjusted analyses (P = .109 and .216). The 2-year patency rates for the LAD site were 98% in the sequential group and 100% in the auto-Y group (P = .195). The 2-year patency rates for the diagonal artery site were 100% in the sequential group and 92.9% in the auto-Y group (P = .038).
Revascularization of the left anterior descending artery area using a single skeletonized left internal thoracic artery resulted in excellent clinical outcomes and graft patency using either auto-Y or sequential grafting. However, there was a higher rate of diagonal branch graft occlusion after auto-Y compared with sequential grafting.
为了最大限度地利用左内乳动脉进行冠状动脉旁路移植术,我们采用了一种策略,即使用单根游离左内乳动脉为左前降支区域进行血运重建;自体 Y 型复合移植和序贯旁路移植。本研究评估了这些手术后的吻合通畅率和临床结果。
2003 年至 2009 年,144 名患者(112 名男性;年龄 62.9±8.9 岁)接受了冠状动脉旁路移植术,使用单根左内乳动脉旁路移植吻合左前降支和对角支。其中,57 名患者行序贯吻合(序贯组),87 名患者行自体 Y 型复合吻合(自体 Y 组)。通过连续多层螺旋 CT 评估吻合通畅率。
无早期死亡。平均随访 66.2±44.5 个月期间,发生 8 例死亡,包括 2 例心源性死亡,无再次介入治疗病例。两组患者在粗死亡率和调整后死亡率方面的风险相似(P=0.109 和 P=0.216)。序贯组和自体 Y 组左前降支的 2 年通畅率分别为 98%和 100%(P=0.195)。序贯组和自体 Y 组对角支的 2 年通畅率分别为 100%和 92.9%(P=0.038)。
使用单根游离左内乳动脉对左前降支区域进行血运重建,无论是自体 Y 型还是序贯吻合,均可获得良好的临床效果和吻合通畅率。然而,与序贯吻合相比,自体 Y 型吻合对角支的闭塞率更高。