Jung Sung-Ho, Song Hyun, Choo Suk Jung, Je Hyung Gon, Chung Cheol Hyun, Kang Joon-Won, Lee Jae Won
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Republic of Korea.
J Thorac Cardiovasc Surg. 2009 Jul;138(1):76-83. doi: 10.1016/j.jtcvs.2008.12.004. Epub 2009 Feb 7.
The radial artery is frequently the second graft of choice after the left internal thoracic artery in coronary artery bypass graft surgery. However, the optimal radial artery proximal anastomosis site remains controversial. The aim of the present study was to compare the radial artery patency according to its use as either an aorta-radial artery graft or composite radial artery graft in coronary artery bypass grafting.
A total of 1735 patients received coronary artery bypass grafting using the radial artery between January 2001 and July 2007, of whom 893 received serial computed tomographic coronary angiographies; these patients formed the basis of the current study. The patients were divided into 2 groups: group I (direct radial artery to aortic anastomosis, n = 451 patients) and group II (radial artery composite grafting with the left internal thoracic artery, n = 442 patients). The number of distal radial artery anastomoses performed in group I was 657 and 749 in group II. Sequential bypassing was performed in 399 patients.
The early patency rate was significantly higher in group I than in group II (98.3% vs 94.5%; P = .004). The 1-, 2-, and 5-year patency rates were also higher in group I than in group II (93.8% +/- 1.2%, 90.5% +/- 1.6%, and 74.3% +/- 6.1%, vs 90.5% +/- 1.4%, 85.3% +/- 1.9%, and 65.2% +/- 4.2%, respectively; P = .004). Multivariate analysis showed composite grafting (P = .02), the degree of target vessel stenosis <90% (P = .001), and the target revascularization site (P = .005) to be significant risk factors for occlusion.
The results of the current data showed superior early and late patency rates of coronary artery bypass grafting with radial artery to aorta anastomosis compared with left internal thoracic artery-radial artery composite grafting.
在冠状动脉旁路移植手术中,桡动脉常常是继左乳内动脉之后的第二选择移植物。然而,桡动脉近端吻合的最佳部位仍存在争议。本研究的目的是比较在冠状动脉旁路移植术中,将桡动脉用作主动脉 - 桡动脉移植物或复合桡动脉移植物时的通畅率。
2001年1月至2007年7月期间,共有1735例患者接受了使用桡动脉的冠状动脉旁路移植术,其中893例接受了系列计算机断层扫描冠状动脉血管造影;这些患者构成了本研究的基础。患者被分为两组:第一组(桡动脉直接与主动脉吻合,n = 451例患者)和第二组(桡动脉与左乳内动脉进行复合移植,n = 442例患者)。第一组进行的桡动脉远端吻合数量为657处,第二组为749处。399例患者进行了序贯搭桥。
第一组的早期通畅率显著高于第二组(98.3%对94.5%;P = .004)。第一组的1年、2年和5年通畅率也高于第二组(分别为93.8%±1.2%、90.5%±1.6%和74.3%±6.1%,对比90.5%±1.4%、85.3%±1.9%和65.2%±4.2%;P = .004)。多因素分析显示复合移植(P = .02)、靶血管狭窄程度<90%(P = .001)和靶血管再血管化部位(P = .005)是闭塞的显著危险因素。
当前数据结果显示,与左乳内动脉 - 桡动脉复合移植相比,桡动脉与主动脉吻合的冠状动脉旁路移植术具有更高的早期和晚期通畅率。