Kageji T, Mizobuchi Y, Nagahiro S, Nakagawa Y, Kumada H
Department of Neurosurgery, Kagawa National Children's Hospital, Kagawa, Japan.
Appl Radiat Isot. 2011 Dec;69(12):1800-2. doi: 10.1016/j.apradiso.2011.03.021. Epub 2011 Mar 21.
The purpose of this study was to compare the radiation dose between long-survivors and non-long-survivors in patients with glioblatoma (GBM) treated with boron neutron capture therapy (BNCT). Among 23 GBM patients treated with BNCT, there were five patients who survived more than three years after diagnosis. The physical and weighted dose of the minimum gross tumor volume (GTV) of long-survivors was much higher than that of non-long survivors with significant statistical differences.
本研究的目的是比较接受硼中子俘获疗法（BNCT）治疗的胶质母细胞瘤（GBM）患者中长生存期患者与非长生存期患者之间的辐射剂量。在23例接受BNCT治疗的GBM患者中，有5例患者在诊断后存活超过三年。长生存期患者最小大体肿瘤体积（GTV）的物理剂量和加权剂量远高于非长生存期患者，差异具有统计学意义。
