Mátrai Zoltán, Tóth László, Saeki Toshiaki, Sinkovics István, Godény Mária, Takeuchi Hideki, Bidlek Mária, Bartal Alexandra, Sávolt Akos, Dorogi Bence, Kásler Miklós
Országos Onkológiai Intézet Általános és Mellkassebészeti Osztály Budapest Ráth György u. 7-9. 1122.
Orv Hetil. 2011 Apr 24;152(17):678-88. doi: 10.1556/OH.2011.29077.
Regional lymph node status is the most important prognostic factor in breast cancer. Sentinel lymph node biopsy is the standard method of axillary staging in early breast cancer patients with clinically negative nodes. Preoperative lymphoscintigraphy might support refining biopsy findings by determining the number and location of sentinel lymph nodes. In aged or overweight patients, in the presence of atypical or extra-axillary lymphatic drainage, non-visualized lymph nodes, or sentinel lymph nodes close to the isotope injection site, detection could be aided by a new, hybrid imaging tool: the single-photon emission computed tomography combined with computed tomography (3D SPECT/CT). For the first time in Hungarian language, authors overview the literature: all 14 English-language articles on the implementation of 3D SPECT/CT in sentinel lymph node detection in breast cancer are included. It is concluded that 3D SPECT/CT increases the success rate and quality of preoperative sentinel node identification, and is capable of providing a more accurate staging of breast cancer patients in routine clinical practice.
区域淋巴结状态是乳腺癌最重要的预后因素。前哨淋巴结活检是临床腋窝淋巴结阴性的早期乳腺癌患者腋窝分期的标准方法。术前淋巴闪烁显像可通过确定前哨淋巴结的数量和位置来辅助完善活检结果。对于老年或超重患者,存在非典型或腋外淋巴引流、淋巴结未显影或前哨淋巴结靠近同位素注射部位的情况,一种新型的混合成像工具——单光子发射计算机断层扫描与计算机断层扫描相结合(3D SPECT/CT)可辅助检测。作者首次用匈牙利语综述文献:纳入了所有14篇关于3D SPECT/CT在乳腺癌前哨淋巴结检测中应用的英文文章。得出的结论是,3D SPECT/CT提高了术前前哨淋巴结识别的成功率和质量,并且能够在常规临床实践中为乳腺癌患者提供更准确的分期。