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10 个月大的早产儿,双侧获得性角膜混浊,行角膜自体和同种异体移植。

Corneal autograft and allograft in a 10-month-old premature boy with acquired bilateral corneal opacities.

机构信息

Mount Sinai School of Medicine, Department of Ophthalmology, New York, NY 10029, USA.

出版信息

Cornea. 2011 Aug;30(8):905-6. doi: 10.1097/ICO.0b013e3182031a72.

Abstract

PURPOSE

To report a case in which corneal autograft and allograft were performed in a 10.5-month-old, ex 24-week, premature boy with bilateral corneal opacities from infectious keratitis.

METHODS

Case report based upon chart review.

RESULTS

At 3 years, the corneal autograft is clear without vascular ingrowth. After transplantation, the clarity of the autograft improved markedly and unexpectedly from its pretransplantation appearance. The child fixes and follows and has central steady maintained fixation at near with a spectacle correction of +11.00 diopters. The allografted cornea is opaque with 360 degrees of vascular ingrowth. This eye is phthisical with no response to light.

CONCLUSIONS

In circumstances in which a viable cornea is available from the patient's worse prognosis eye, a corneal autograft is a potential treatment option.

摘要

目的

报告一例 10.5 月龄、孕 24 周早产儿,因感染性角膜炎致双眼角膜混浊,行角膜自体和同种异体移植的病例。

方法

基于病历回顾的病例报告。

结果

3 岁时,角膜自体移植物透明,无血管侵入。移植后,自体移植物的透明度明显改善,出乎意料地恢复到移植前的外观。患儿可固视和追随,近距中央稳定固视,矫正远视+11.00 屈光度。同种异体移植角膜混浊,360 度血管侵入。这只眼睛已经萎缩,对光无反应。

结论

在患者预后较差的眼睛中有可用的健康角膜的情况下,角膜自体移植是一种潜在的治疗选择。

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