Umeh R E, Babalola O E, Mahmoud A O, Okoye O I, Asana U E, Umeh C N, Braide E, Biritwum R, Seketeli A
College of Medicine, University of Nigeria, Enugu Campus, Nigeria.
West Afr J Med. 2010 Nov-Dec;29(6):412-6.
Non-invasive tool of community diagnosis for onchocercal endemicity needs to be identified and ascertained for their utility and effectivity in order to facilitate the control of onchocerciacis in sub-Saharan Africa
To determine the utility and effectiveness of the Wu-Jones Motion Sensitivity Screening Test (MSST) in detecting optic nerve diseases in onchocercal-endemic rural Africa.
MSST was applied to sampled subjects in the selected communities of Raja in Sudan; Bushenyi in Uganda; Morogoro in Tanzania; and of Ikom, Olamaboro and Gashaka in Nigeria. Basically, six points within the central field of vision were repeatedly tested at 1/3 meter from the screen of a laptop computer in a room darkened. Motion sensitivity was expressed as a percentage of motion detected in the individual eye and this was averaged for the community.
A total of 3,858 eyes of 2,072 patients were examined. Seventy-six percent of the subjects completed the test, at an average test time of 120.4 (66.7) seconds. The overall mean motion sensitivity of all eyes tested was 88.49 (17.49%). At a cut-off point of 50%, 6.4% of all subjects tested were subnormal, while at 70% cutoff, 13.3% were subnormal. The highest proportion of 50% cutoff sub-normality was recorded at Morogoro at 12.7%.
Motion Sensitivity Screening Test was widely accepted and easily administered to the rural and largely illiterate subjects studied. Our data suggest that the proportion of severe field defects by MSST in a community, with cutoff at 33%, best correlates with optic nerve disease prevalence, while proportion of defect from a higher cut-off level at about 50%, best correlates with overall ocular morbidity.
需要确定用于盘尾丝虫病流行情况社区诊断的非侵入性工具，并评估其效用和有效性，以便在撒哈拉以南非洲推动盘尾丝虫病的防治工作。
确定吴-琼斯运动敏感性筛查试验（MSST）在非洲盘尾丝虫病流行的农村地区检测视神经疾病的效用和有效性。
在苏丹的拉贾、乌干达的布申尼、坦桑尼亚的莫罗戈罗以及尼日利亚的伊科姆、奥拉马博罗和加沙卡等选定社区对抽样对象进行MSST检测。基本上，在暗室中，在距离笔记本电脑屏幕1/3米处对中央视野内的六个点进行反复测试。运动敏感性以单眼检测到的运动百分比表示，并对社区数据求平均值。
共检查了2072名患者的3858只眼睛。76%的受试者完成了测试，平均测试时间为120.4（66.7）秒。所有受试眼睛的总体平均运动敏感性为88.49（17.49%）。在临界值为50%时，所有受试对象中有6.4%低于正常水平，而在临界值为70%时，13.3%低于正常水平。在莫罗戈罗记录到临界值为50%时低于正常水平的比例最高，为12.7%。
运动敏感性筛查试验被广泛接受，且易于应用于所研究的农村及大部分为文盲的受试者。我们的数据表明，在社区中，MSST检测出的严重视野缺损比例（临界值为33%）与视神经疾病患病率的相关性最佳，而临界值约为50%时的缺损比例与总体眼部发病率的相关性最佳。
