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β2受体激动拟交感神经药(NAB 365)用于患有呼吸道疾病马匹的兽医临床经验(作者译)

[Veterinary and clinical experience of the use of a beta2-receptor-stimulating sympathicomimetic agent (NAB 365) in horses with respiratory discase (author's transl)].

作者信息

Sasse H H, Hajer R

出版信息

Tijdschr Diergeneeskd. 1977 Nov 1;102(21):1233-8.

PMID:21467
Abstract

The manufacturers state that NAB 365 is a beta2-receptor-stimulating sympathicomimetic agent. According to the medical literature it combines a bronchial antispasmodic effect with certain bronchia secretolytic properties and has few untoward side-effects on, for instance, the heart and intestine. The effectiveness of administration of NAB 365 in horses with chronic or acute respiratory disease was tested in the Department of Veterinary Internal medicine in Utrecht. NAB 365 administered at a dosage of 0.8 gamma/kg, of body weight was found to have a marked bronchodilative effect in horses. There was also evidence of a bronchialsecretolytic effect. NAB 365 has a beneficial effect on respiration. At a dosage of 0.8 gamma/kg of body weight, twice daily, there are few side-effects, even when administration is continued for a fortnight. The clinical effect on respiration continued practically throughout the day.

摘要

制造商称NAB 365是一种刺激β2受体的拟交感神经药。根据医学文献,它兼具支气管解痉作用和一定的支气管溶纤特性,并且对心脏和肠道等几乎没有不良副作用。乌得勒支兽医学内科对NAB 365用于患有慢性或急性呼吸道疾病马匹的有效性进行了测试。发现以0.8微克/千克体重的剂量给马施用NAB 365时,对马有显著的支气管扩张作用。也有证据表明其具有支气管溶纤作用。NAB 365对呼吸有有益作用。以0.8微克/千克体重的剂量,每日两次给药,即使持续给药两周也几乎没有副作用。对呼吸的临床效果几乎持续一整天。

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