Department of Respiratory Medicine, Kyoto University, Kyoto, Japan.
Department of Respiratory Medicine, Kyoto University, Kyoto, Japan.
Chest. 2011 Apr;139(4):930-932. doi: 10.1378/chest.10-1105.
CT scanning allows assessment of airway-wall thickness and is useful for diagnosing and assessing various lung diseases, including asthma and COPD. Several studies have reported that CT scan-estimated dimensions are positively correlated with pulmonary function test results and a positive response to treatment. However, to our knowledge, airway disease complicated by inflammatory bowel disease has not yet been assessed using CT scan-estimated dimensions. A 61-year-old woman with ulcerative colitis (UC) complained of cough, sputum, and fever 4 months after undergoing a total colectomy and rectal mucosectomy. Examination of bronchial biopsy samples demonstrated lymphocytic and plasma cell infiltration of the epithelium and submucosa. CT scan-estimated dimensions indicated thickening of the airways. Chronic bronchitis complicated with UC was diagnosed, and high-dose inhaled corticosteroid therapy was prescribed. Three months later, the CT scan-estimated dimensions of the patient's airways, her symptoms, and pulmonary function test results were dramatically improved.
CT 扫描可评估气道壁厚度，有助于诊断和评估各种肺部疾病，包括哮喘和 COPD。多项研究报告称，CT 扫描估计的尺寸与肺功能测试结果和治疗反应呈正相关。然而，据我们所知，尚未使用 CT 扫描估计的尺寸评估伴有炎症性肠病的气道疾病。一名 61 岁女性患有溃疡性结肠炎（UC），在接受全结肠直肠黏膜切除术 4 个月后出现咳嗽、咳痰和发热。支气管活检样本检查显示上皮和黏膜下层有淋巴细胞和浆细胞浸润。CT 扫描估计的气道尺寸显示气道增厚。诊断为并发溃疡性结肠炎的慢性支气管炎，并开具了高剂量吸入皮质类固醇治疗。三个月后，患者气道的 CT 扫描估计尺寸、症状和肺功能测试结果均显著改善。
