复发性单纯疱疹性脑炎导致克-布综合征。

Relapsing herpes simplex encephalitis resulting in Kluver-Bucy syndrome.

作者信息

Ku Bon D, Yoon Sung Sang

机构信息

Department of Neurology, Myongji Hospital, Kwandong University College of Medicine, Republic of Korea.

出版信息

Intern Med. 2011;50(7):763-6. doi: 10.2169/internalmedicine.50.4792. Epub 2011 Apr 1.

DOI:10.2169/internalmedicine.50.4792

PMID:21467713

Abstract

Relapsing herpes simplex encephalitis (HSE) rarely occurs after acyclovir treatment. We treated a patient with relapsing HSE of the contralateral temporal lobe, resulting in Klüver-Bucy syndrome, after a full-dose acyclovir treatment. This case suggests that physicians should consider sudden behavioral and emotional changes after HSE treatment as a possible indication of relapsing HSE, as well as possible temporal lobe epilepsy, and the need to administer longer acyclovir treatment for select patients.

摘要

复发性单纯疱疹性脑炎（HSE）在接受阿昔洛韦治疗后很少发生。我们治疗了一名在接受全剂量阿昔洛韦治疗后出现对侧颞叶复发性HSE并导致克-布综合征的患者。该病例提示，医生应将HSE治疗后突然出现的行为和情绪变化视为复发性HSE以及可能的颞叶癫痫的一种可能迹象，以及对部分患者进行更长疗程阿昔洛韦治疗的必要性。