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克吕弗-布西综合征——单纯疱疹性脑炎的一种罕见并发症。

Kluver-Bucy syndrome--a rare complication of herpes simplex encephalitis.

作者信息

Begum Hosenara, Nayek Kaustav, Khuntdar Bidyut Kr

机构信息

Department of Paediatrics, Medical College, Kolkata.

出版信息

J Indian Med Assoc. 2006 Nov;104(11):637-8.

Abstract

A twelve-year-old female was admitted with history of high fever, recurrent vomiting and repeated convulsion for 2 days and altered consciousness for one day. Cranial CT scan showed intraparenchymal haemorrhage involving both temporal lobes and right basal ganglia region without mass effect. Serology was reactive against IGM HSV1. Injection acyclovir was started at a dose of 10 mg/kg 8 hourly intravenously. Patient regained consciousness on fourth day but speech was altered. Abnormal behavioural symptoms were noticed. EEG showed generalised spike and slow waves and sharp and slow wave discharge more in the temporal region. The patient was given clonidine and carbamazepine. She also received behavioural therapy and parental counselling. She was followed up for six months and maintaining well.

摘要

一名12岁女性因高热、反复呕吐和抽搐2天、意识改变1天入院。头颅CT扫描显示双侧颞叶及右侧基底节区脑实质内出血,无占位效应。血清学检测对IGM HSV1呈阳性反应。开始静脉注射阿昔洛韦,剂量为10mg/kg,每8小时一次。患者在第四天恢复意识,但言语出现改变,伴有异常行为症状。脑电图显示广泛性棘波和慢波,颞区尖慢波放电增多。给予患者可乐定和卡马西平治疗,同时接受行为治疗和家长咨询。对其进行了6个月的随访,患者情况良好。

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