Oknina L B, Kuznetsova O A, Belostostskiĭ A P, Nechaeva N L, Kutakova E V, Masherov E L, Romanov A S
Fiziol Cheloveka. 2011 Jan-Feb;37(1):56-64.
The aim of study was to track a cumulative changes of amplitude-time parametres of components N1, N2 and P300 of acoustic evoked potential in experimental situations different in complexity (at the account and listening of sounds) and to compare the received distinctions at examinees of young and mature age. ERP were recorded at 12 healthy subjects from 18 to 22 ages and 12 subjects from 32 to 59 ages. The two-stimuli oddball paradigm was used. It is revealed that components N1, N2 and P300 recorded in the situation of the listenings of sounds without any preliminary instruction do not differ at persons of young and mature age. At examinees of younger age the biger amplitude of component N1 is noted at the account of sounds in comparison with listening whereas the latency of the one do not change depending on complexity of the task. It is shown that component N2 has stability of latency in relation to age and an experimental situation. The amplitude of component N2 is above at the account of sounds in both age groups. The amplitude-time parametres of component P300 do not differ at examinees of different age in a problem of listening of sounds. The revealed features of components N1, N2 and P300 at examinees of young and mature age in experimental situations different in complexity, allow to assume that with the years at the person adaptive mechanisms which allow carrying out successfully of the task.
本研究的目的是追踪在复杂度不同（计数和听声音）的实验情境中，听觉诱发电位的N1、N2和P300成分的幅度-时间参数的累积变化，并比较年轻和成年受试者所得到的差异。对12名年龄在18至22岁的健康受试者和12名年龄在32至59岁的受试者记录了事件相关电位（ERP）。采用双刺激Oddball范式。结果显示，在没有任何预先指导的听声音情境中记录的N1、N2和P300成分在年轻和成年个体中没有差异。在较年轻的受试者中，与听声音相比，计数声音时N1成分的幅度更大，而其潜伏期不随任务复杂度而变化。结果表明，N2成分的潜伏期在年龄和实验情境方面具有稳定性。两个年龄组在计数声音时N2成分的幅度都更高。在听声音问题上，不同年龄受试者的P300成分的幅度-时间参数没有差异。在年轻和成年受试者中，在复杂度不同的实验情境下所揭示的N1、N2和P300成分的特征，使得可以假设随着年龄增长，个体具有能够成功完成任务的适应性机制。
