Department of Simulations and Graphics, O.v.G. University Magdeburg, Berlin, Germany.
Bioinformatics. 2011 Jun 1;27(11):1573-4. doi: 10.1093/bioinformatics/btr163. Epub 2011 Apr 5.
Contact maps are a valuable visualization tool in structural biology. They are a convenient way to display proteins in two dimensions and to quickly identify structural features such as domain architecture, secondary structure and contact clusters. We developed a tool called CMView which integrates rich contact map analysis with 3D visualization using PyMol. Our tool provides functions for contact map calculation from structure, basic editing, visualization in contact map and 3D space and structural comparison with different built-in alignment methods. A unique feature is the interactive refinement of structural alignments based on user selected substructures.
CMView is freely available for Linux, Windows and MacOS. The software and a comprehensive manual can be downloaded from http://www.bioinformatics.org/cmview/. The source code is licensed under the GNU General Public License.
接触图是结构生物学中一种有价值的可视化工具。它们是在二维空间中展示蛋白质的一种便捷方式,可以快速识别结构特征,如结构域架构、二级结构和接触簇。我们开发了一种名为 CMView 的工具,它将丰富的接触图分析与使用 PyMol 的 3D 可视化相结合。我们的工具提供了从结构计算接触图、基本编辑、在接触图和 3D 空间中可视化以及使用不同内置对齐方法进行结构比较的功能。一个独特的功能是基于用户选择的子结构进行交互式结构对齐精修。
CMView 可免费用于 Linux、Windows 和 MacOS。软件和综合手册可从 http://www.bioinformatics.org/cmview/ 下载。源代码根据 GNU 通用公共许可证获得许可。