Gritti Paolo, Lanterna Luigi A, Chinaglia Daniela, Manara Ornella, Soavi Laura, Zilio Anna, Suter Fredy
Department of Neuroscience, Anaesthesia and Intensive Care IV, Ospedali Riuniti di Bergamo, Italy.
Infez Med. 2011 Mar;19(1):45-8.
We report on a patient who presented at our hospital with fever, headache, neck pain, partial nuchal rigidity and decreased vision of the left eye. The clinical history, biochemical and instrumental exams performed suggested meningitis but the final hypothesis achieved was an unusual case of Neuro-Behcet-Disease (NBD) without orogenital ulcerations at presentation and with normal MRI findings, whose course was complicated by fatal cerebral venous sinus thrombosis and intracranial haemorrhage. The post-mortem results confirmed the diagnosis. This is a rare case confirmed by anatomo-pathological findings where NBD can present itself as an acute meningeal syndrome that mimics central nervous system infections, making diagnosis difficult and delaying treatment.
我们报告了一名患者，该患者因发热、头痛、颈部疼痛、颈部部分强直及左眼视力下降前来我院就诊。所进行的临床病史、生化及器械检查提示为脑膜炎，但最终确诊为一例罕见的神经白塞病（NBD），其发病时无口生殖器溃疡且MRI检查结果正常，病程中并发致命的脑静脉窦血栓形成及颅内出血。尸检结果证实了诊断。这是一例经解剖病理学检查结果证实的罕见病例，其中NBD可表现为类似中枢神经系统感染的急性脑膜综合征，导致诊断困难并延误治疗。
