Kawanishi Y, Hori T, Suzuki T, Mizukami K, Sasaki M, Shiraishi H
Psychiatric Service, University of Tsukuba Hospital, Ibaraki, Japan.
Psychiatry Clin Neurosci. 1995 Dec;49(5-6):263-6. doi: 10.1111/j.1440-1819.1995.tb01899.x.
The case of a 50 year old man with personality changes, dementia, and brain stem symptoms is presented. Magnetic resonance imaging (MRI) disclosed high signal areas mainly in the brain stem. Both a positive skin prick test and an HLA-B51 were demonstrated. These clinical findings were suggestive of neuro-Behçet syndrome, although there were no mucocutaneo-ocular symptoms characteristically associated with this disease. The relationship between neuro-Behçet syndrome and brain stem encephalitis, including a discrimination from multiple sclerosis, is discussed.