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胸锁乳突肌肌瓣预防腮腺切除术后弗雷综合征的系统评价。

Sternocleidomastoid muscle flap in preventing Frey's syndrome after parotidectomy: a systematic review.

机构信息

Department of Surgery, Universidad de La Sabana-Fundacion Abood Shaio, Bogota, Colombia.

出版信息

Head Neck. 2012 Apr;34(4):589-98. doi: 10.1002/hed.21722. Epub 2011 Apr 5.

Abstract

BACKGROUND

Parotidectomy is a common procedure and Frey's syndrome (gustatory sweating) is a common side effect. The current literature was assessed concerning the effectiveness of the sternocleidomastoid muscle (SCM) flap to prevent Frey's syndrome after parotidectomy.

METHODS

A bibliography search was conducted for studies published between 1966 and 2010 and included randomized controlled trials (RCTs) or cohort studies with patients undergoing parotidectomy with facial nerve preservation. The outcome measures of particular interest were the incidence of Frey's syndrome and cosmetic impairment.

RESULTS

In all, 12 studies were selected (1 meta-analysis of all interventions to prevent Frey's syndrome, 2 RCTs, and 9 cohort studies). The trials were too heterogeneous to perform a meta-analysis on the effect of the SCM flap. The results reported by the authors of each study suggest an objective decrease in Frey's syndrome when the SCM flap was used, but there was no difference in the patients' subjective reporting of symptoms. However, this conclusion is prone to the biases inherent in these studies, and thus overall it is impossible to make any recommendation.

CONCLUSION

Current reported evidence is inconclusive as to the use of SCM muscle flap as an intervention to prevent Frey's syndrome following parotid surgery.

摘要

背景

腮腺切除术是一种常见的手术,而弗雷氏综合征(味觉性出汗)是一种常见的副作用。目前的文献评估了胸锁乳突肌(SCM)皮瓣在预防腮腺切除术后弗雷氏综合征方面的有效性。

方法

对 1966 年至 2010 年期间发表的研究进行了文献检索,包括随机对照试验(RCT)或队列研究,这些研究的对象是接受面神经保留的腮腺切除术患者。特别关注的结局指标是弗雷氏综合征和美容损害的发生率。

结果

共选择了 12 项研究(1 项针对所有预防弗雷氏综合征干预措施的荟萃分析、2 项 RCT 和 9 项队列研究)。由于试验的异质性太大,无法对 SCM 皮瓣的效果进行荟萃分析。每个研究作者报告的结果表明,使用 SCM 皮瓣可客观降低弗雷氏综合征的发生率,但患者对症状的主观报告无差异。然而,这一结论容易受到这些研究中固有的偏倚的影响,因此总体上无法提出任何建议。

结论

目前关于 SCM 肌肉瓣作为预防腮腺手术后弗雷氏综合征的干预措施的使用的报告证据尚无定论。

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