Department of Otorhinolaryngology, Head and Neck Surgery, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany.
Head Neck. 2012 Mar;34(3):371-5. doi: 10.1002/hed.21742. Epub 2011 Apr 5.
Biopsy and histological examination of persistently enlarged cervical lymph nodes represent a major health care issue and have high impact on further clinical therapy. Tertiary health centers are faced with an increased demand for diagnostic workup to rule out malignancy. We performed a retrospective study from January 2000 to June 2008 to identify patients referred to us for diagnostic biopsy and to document the histopathological result.
Patients with a diagnostic biopsy, but neither clinical signs of head and neck cancer nor other malignancies, were identified within the records. Patient characteristics and histopathological diagnosis were retrieved.
Three hundred twenty-six patients were identified (146 women, and 180 men). One hundred twenty-three patients (38%; 44 women, and 79 men) had a malignancy: 61 with metastatic disease and 62 with malignant lymphoma; the youngest was 15 years old and the oldest was 92 years old.
Persistently swollen cervical lymph nodes should trigger a thorough clinical examination and prompt biopsy for histopathological workup.
持续肿大的颈淋巴结活检和组织学检查是一个主要的医疗保健问题，对进一步的临床治疗有很大的影响。三级保健中心面临着越来越多的诊断工作需求，以排除恶性肿瘤。我们进行了一项回顾性研究，从 2000 年 1 月至 2008 年 6 月，确定了转介到我们这里进行诊断性活检的患者，并记录了组织病理学结果。
在病历中确定了接受诊断性活检但无头颈部癌症或其他恶性肿瘤临床迹象的患者。检索了患者的特征和组织病理学诊断。
共确定了 326 例患者（女性 146 例，男性 180 例）。123 例（38%；女性 44 例，男性 79 例）患有恶性肿瘤：61 例为转移性疾病，62 例为恶性淋巴瘤；最小年龄为 15 岁，最大年龄为 92 岁。
持续肿大的颈淋巴结应引起彻底的临床检查，并及时进行组织病理学检查。
