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[从血液中分离出的大肠杆菌菌株的分离频率及对抗生素的敏感性]

[Frequency of isolation and susceptibility to antibiotics of Escherichia coli strains isolated from blood].

作者信息

Białucha Agata, Budzyńska Anna, Kozuszko Sylwia, Gospodarek Eugenia

机构信息

Katedra i Zakład Mikrobiologii Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytetu Mikołaja Kopernika w Toruniu.

出版信息

Med Dosw Mikrobiol. 2010;62(4):337-43.

Abstract

The aim of our study was the analysis of Escherichia coli strains obtained from patients of University Hospital No 1 of dr A. Jurasz Collegium Medicum of L. Rydygier in Bydgoszcz Nicolaus Copernicus University in Toruń and State Infectious Diseases Observatory Hospital of T. Browicz in Bydgoszcz, between 2007 and 2010. Among all microorganisms isolated from blood was 8.7% E. coli strains and 45.1% of all rods from Enterobacteriaceae family. Number of E. coli isolations from positive blood samples was: 64 in 2007, 69 in 2008, 77 in 2009 and 26 in the first half of 2010 year. The highest percentage of E. coli strains were obtained from patients of the Transplantology and Surgery Clinic (16.1%), the Nephrology and Internal Diseases Clinic with the Dialysis Centre (14.0%), the Pediatric, Hematology and Oncology Clinic (13.6%) and the Anesthesiology and Intensive Care Clinic (13.6%). All analysed strains were susceptible to carbapenems, amikacin and tygecycline. The highest percentage of resistant strains were observed to ampicillin (70.7%), piperacillin (43.9%), tetracycline (42.8%) and doxycycline (38.8%). During four years of study 4 (6.3%), one, three and two E. coli strains with ESBL were isolated, respectively.

摘要

我们研究的目的是分析2007年至2010年间从位于比得哥什的A. 尤拉什医学院附属第一大学医院(隶属于托伦哥白尼大学)以及位于比得哥什的T. 布罗维茨国家传染病观察医院的患者身上分离出的大肠杆菌菌株。在从血液中分离出的所有微生物中,大肠杆菌菌株占8.7%,肠杆菌科所有杆菌占45.1%。从阳性血样中分离出的大肠杆菌数量分别为:2007年64株,2008年69株,2009年77株,2010年上半年26株。大肠杆菌菌株比例最高的是从移植与外科诊所(16.1%)、设有透析中心的肾脏病与内科诊所(14.0%)、儿科、血液学与肿瘤诊所(该英文表述有误,正确的应该是Pediatric, Hematology and Oncology Clinic,13.6%)以及麻醉与重症监护诊所(13.6%)的患者身上获得的。所有分析的菌株对碳青霉烯类、阿米卡星和替加环素敏感。观察到耐药菌株比例最高的是氨苄西林(70.7%)、哌拉西林(43.9%)、四环素(42.8%)和多西环素(38.8%)。在四年的研究期间,分别分离出4株(6.3%)、1株、3株和2株产超广谱β-内酰胺酶(ESBL)的大肠杆菌菌株。

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