Department of Rheumatology, Pierre and Marie Curie University, APHP Saint-Antoine Hospital, Paris, France.
Ann Rheum Dis. 2011 Aug;70(8):1354-6. doi: 10.1136/ard.2010.146399. Epub 2011 Apr 6.
Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA), at least in some patients, leading to the concept of a diabetes-induced OA phenotype. If confirmed, this new paradigm will have a dramatic impact on prevention of OA initiation and progression.
一些流行病学和实验数据支持这样一种假说,即糖尿病可能是骨关节炎(OA)的一个独立危险因素,至少在某些患者中是这样,这导致了糖尿病诱导的 OA 表型的概念。如果得到证实,这一新的范式将对预防 OA 的发生和进展产生巨大影响。