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个体音乐治疗抑郁症:随机对照试验。

Individual music therapy for depression: randomised controlled trial.

机构信息

GAMUT, Uni Health, Lars Hilles gt. 3, 5015 Bergen, Norway.

出版信息

Br J Psychiatry. 2011 Aug;199(2):132-9. doi: 10.1192/bjp.bp.110.085431. Epub 2011 Apr 7.

Abstract

BACKGROUND

Music therapy has previously been found to be effective in the treatment of depression but the studies have been methodologically insufficient and lacking in clarity about the clinical model employed. Aims To determine the efficacy of music therapy added to standard care compared with standard care only in the treatment of depression among working-age people.

METHOD

Participants (n = 79) with an ICD-10 diagnosis of depression were randomised to receive individual music therapy plus standard care (20 bi-weekly sessions) or standard care only, and followed up at baseline, at 3 months (after intervention) and at 6 months. Clinical measures included depression, anxiety, general functioning, quality of life and alexithymia.

TRIAL REGISTRATION

ISRCTN84185937.

RESULTS

Participants receiving music therapy plus standard care showed greater improvement than those receiving standard care only in depression symptoms (mean difference 4.65, 95% CI 0.59 to 8.70), anxiety symptoms (1.82, 95% CI 0.09 to 3.55) and general functioning (-4.58, 95% CI -8.93 to -0.24) at 3-month follow-up. The response rate was significantly higher for the music therapy plus standard care group than for the standard care only group (odds ratio 2.96, 95% CI 1.01 to 9.02).

CONCLUSIONS

Individual music therapy combined with standard care is effective for depression among working-age people with depression. The results of this study along with the previous research indicate that music therapy with its specific qualities is a valuable enhancement to established treatment practices.

摘要

背景

音乐疗法已被证明在治疗抑郁症方面有效,但这些研究在方法上不够充分,并且对于所采用的临床模式也不够明确。目的:确定与仅接受标准护理相比,在治疗工作年龄人群的抑郁症时,添加音乐疗法对标准护理的疗效。

方法

参与者(n = 79)根据 ICD-10 诊断患有抑郁症,被随机分配接受个体音乐治疗加标准护理(20 次双周疗程)或仅接受标准护理,并在基线、3 个月(干预后)和 6 个月进行随访。临床评估包括抑郁、焦虑、一般功能、生活质量和述情障碍。

试验注册

ISRCTN84185937。

结果

与仅接受标准护理相比,接受音乐治疗加标准护理的参与者在抑郁症状(平均差异 4.65,95%置信区间 0.59 至 8.70)、焦虑症状(1.82,95%置信区间 0.09 至 3.55)和一般功能(-4.58,95%置信区间-8.93 至-0.24)方面在 3 个月随访时显示出更大的改善。音乐治疗加标准护理组的反应率明显高于仅接受标准护理组(优势比 2.96,95%置信区间 1.01 至 9.02)。

结论

个体音乐疗法结合标准护理对工作年龄人群的抑郁症有效。本研究结果与之前的研究一起表明,具有特定品质的音乐疗法是对既定治疗实践的有价值的增强。

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