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[乙肝表面抗原阳性母亲与新生儿免疫:特拉帕尼第一地方卫生单位的经验]

[HBsAG-positive mothers and neonatal immunization: experience at the USL No. 1 in Trapani].

作者信息

Bonanno Conti M I, Critti A F, La Rocca S, Rappa A R

机构信息

Divisione di Neonatologia e Terapia Intensiva Neonatale dell'Ospedale S. Antonio Abate di Trapani.

出版信息

Minerva Pediatr. 1990 Jun;42(6):233-5.

PMID:2147456
Abstract

A vaccination campaign against HBV was undertaken by the Division of Neonatal Pathology at the Hospital of Trapani from 1984 to 1989 with the aim of reducing morbidity and mortality rates due to HBV. 6,849 women were studied in order of HBV diagnosis. Seventy-four of these (1.08%) were HBsAg positive, and 4/74 were HBeAg positive. Seventy-two high-risk newborns underwent passive immunoprophylaxis and a vaccination cycle. Antibody titres demonstrated the effectiveness of therapy in 95.1% of subjects.

摘要

1984年至1989年,特拉帕尼医院新生儿病理科开展了一项针对乙肝病毒(HBV)的疫苗接种运动,旨在降低因HBV导致的发病率和死亡率。按照HBV诊断顺序对6849名女性进行了研究。其中74名(1.08%)为乙肝表面抗原(HBsAg)阳性,4/74为乙肝e抗原(HBeAg)阳性。72名高危新生儿接受了被动免疫预防和一个疫苗接种周期。抗体滴度显示95.1%的受试者治疗有效。

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