体外硼草（Borago officinalis）提取物对溶组织内阿米巴的杀阿米巴活性。
In vitro amoebicidal activity of borage (Borago officinalis) extract on Entamoeba histolytica.
机构信息
Faculty of Biological Sciences, Universidad Autonoma de Nuevo Leon, Pedro de Alba y Manuel L. Barragan, Ciudad Universitaria, San Nicolas de los Garza, Nuevo Leon, Mexico.
出版信息
J Med Food. 2011 Jul-Aug;14(7-8):866-9. doi: 10.1089/jmf.2010.0164. Epub 2011 Apr 10.
Borage (Borago officinalis) is a plant with nutritional value that is also used in traditional medicine to treat gastrointestinal disease. This study investigated the amoebicidal activity of a methanol extract of borage. The 50% inhibitory concentration (IC₅₀) of the extract for Entamoeba histolytica was 33 μg/mL. The 50% lethal dose of the extract for brine shrimp was greater than 1,000 μg/mL. The IC₅₀ of the extract for Vero cells was 203.9 μg/mL. These results support the use of borage to prevent diseases associated with E. histolytica infection.
琉璃苣（Borago officinalis）是一种具有营养价值的植物，也在传统医学中用于治疗胃肠道疾病。本研究调查了琉璃苣甲醇提取物的杀变形虫活性。该提取物对溶组织内阿米巴的 50%抑制浓度（IC₅₀）为 33μg/mL。该提取物对卤虫的 50%致死剂量大于 1000μg/mL。该提取物对 Vero 细胞的 IC₅₀为 203.9μg/mL。这些结果支持使用琉璃苣来预防与溶组织内阿米巴感染相关的疾病。
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