Aiello A, Cristofaro M, Carrozza F, Verdone F, Carile L
Divisione di Medicina Generale, U.S.L. N. 5, Ospedale Regionale di Campobasso.
Clin Ter. 1990 Jun 30;133(6):401-4.
There are no univocal experimental data in literature about T cell clone alterations in the peripheral blood during Hashimoto's thyroiditis (TH), autoimmune disease, and during subacute thyroiditis (TSA), an inflammatory thyroid lesion with possibility of "self-perpetuation". The object of our research was to examine the T cell clones, soluble fraction of interleukin 2 receptor and HLA-DR modifications in patients with TH and TSA compared with healthy population. Our results show significant increase of sIL-2r in the TSA compared with normal subjects and with patients TH, where on the contrary, a constant increase of HLA-DR was observed.
关于桥本甲状腺炎（TH）（一种自身免疫性疾病）以及亚急性甲状腺炎（TSA）（一种可能“自我延续”的炎症性甲状腺病变）期间外周血中T细胞克隆改变，文献中没有明确的实验数据。我们研究的目的是检测TH和TSA患者与健康人群相比的T细胞克隆、白细胞介素2受体可溶性部分和HLA - DR修饰情况。我们的结果显示，与正常受试者和TH患者相比，TSA患者的sIL - 2r显著增加，而TH患者则观察到HLA - DR持续增加。
