用光声检测监测受激拉曼散射。
Monitoring stimulated Raman scattering with photoacoustic detection.
机构信息
Department of Physics, University of Wisconsin-Milwaukee, 1900 E. Kenwood Boulevard, Milwaukee, Wisconsin 53211, USA.
出版信息
Opt Lett. 2011 Apr 1;36(7):1233-5. doi: 10.1364/OL.36.001233.
Abstract
A capability of high-frequency ultrasound detection to monitor the process of energy deposition into a molecular system via Raman excitation is experimentally demonstrated. It is shown that the generated ultrasound signal is directly proportional to the optical signal generated in stimulated Raman scattering. Ultrasound detection provides a simple way to discriminate against laser-induced breakdown and allows for the quantification of the stimulated Raman scattering process where direct optical detection is not available. Additionally, it can be used for stimulated Raman imaging in deep tissue, provided that the generated photoacoustic signal is sufficiently strong.
摘要
高频超声检测技术可用于监测通过喇曼激发实现的能量沉积过程，实验证明了这一技术的可行性。实验结果表明，产生的超声信号与受激喇曼散射中产生的光学信号成正比。超声检测提供了一种简单的方法来区分激光诱导击穿，并可对直接光学检测不可用的受激喇曼散射过程进行定量分析。此外，只要产生的光声信号足够强，它就可用于深层组织中的受激喇曼成像。
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