Department of Chemical and Process Engineering, University of Strathclyde, 75 Montrose Street, Glasgow G1 1XJ, UK.
Chem Commun (Camb). 2011 Jul 21;47(27):7567-82. doi: 10.1039/c0cc05648k. Epub 2011 Apr 11.
In a previous review of biological and bioinspired silica formation (S. V. Patwardhan et al., Chem. Commun., 2005, 1113 [ref. 1]), we have identified and discussed the roles that organic molecules (additives) play in silica formation in vitro. Tremendous progress has been made in this field since and this review attempts to capture, with selected examples from the literature, the key advances in synthesising and controlling properties of silica-based materials using bioinspired approaches, i.e. conditions of near-neutral pH, all aqueous environments and room temperature. One important reason to investigate biosilicifying systems is to be able to develop novel materials and/or technologies suitable for a wide range of applications. Therefore, this review will also focus on applications arising from research on biological and bioinspired silica. A range of applications such as in the areas of sensors, coatings, hybrid materials, catalysis and biocatalysis and drug delivery have started appearing. Furthermore, scale-up of this technology suitable for large-scale manufacturing has proven the potential of biologically inspired synthesis.
在之前关于生物和仿生二氧化硅形成的综述中（S. V. Patwardhan 等人，Chem. Commun.，2005，1113 [参考文献 1]），我们已经确定并讨论了有机分子（添加剂）在体外二氧化硅形成中所起的作用。自那时以来，该领域取得了巨大的进展，本综述试图通过文献中的精选示例，捕捉使用仿生方法合成和控制基于二氧化硅的材料的关键进展，即接近中性 pH 值、全水相环境和室温的条件。研究生物硅化系统的一个重要原因是能够开发适用于广泛应用的新型材料和/或技术。因此，本综述还将重点关注生物和仿生二氧化硅研究带来的应用。一系列应用，如传感器、涂层、杂化材料、催化和生物催化以及药物输送，已经开始出现。此外，适合大规模制造的这种技术的规模化已经证明了仿生合成的潜力。
