Gökçe Selim, Durmaz Ozlem, Peykerlı Gürsu Gülcan, Aydoğan Ayşen, Celtık Coşkun, Ozden Ilgin, Sökücü Semra
Department of Pediatric Gastroenterology, İstanbul University, İstanbul School of Medicine, İstanbul.
Turk J Gastroenterol. 2011 Feb;22(1):36-41.
BACKGROUND/AIMS: We aimed in this study to investigate pre- and posttransplant clinical and psychosocial features of the donors and the effects of living-related liver transplantation and possible relevant factors on psychosocial outcome and family functioning.
Thirty-two living donors (19 females, age 31.84 ± 7.10 years) were evaluated. Medical records of donors regarding pre- and posttransplant clinical and psychological features and family life were evaluated.
The donors were parents (n=28, 87.6%) in most. In the pretransplant evaluation, 5 donors (19.3%) had anxiety regarding postoperative complications and quality of life. Donors were discharged from the hospital in a median of 7 days (range, 5-30 days). Return to work and feeling of complete well-being were accomplished in a median of 4 weeks (range, 1-32 weeks) and 10 weeks (range, 4-48 weeks), respectively. Sixteen recipients (50.0%) suffered from major complications, and 3 (9.4%) required invasive intervention. Fourteen donors (43.4%) reported pain around the surgical incision and nonspecific gastrointestinal problems postoperatively. Psychological problems were observed in 8 donors (25.0%); 2 (6.3%) had depression requiring drug and psychotherapeutic intervention. Psychological disruption was found to be correlated with the presence of problems in the recipient (p<0.01, r=0.487). The donors' relationship with the recipient was negatively affected in 1 (3.1%), but improved in 15 (46.9%) cases. Nine donors (34.6%) displayed nervous behavior toward their spouses, and 2 (7.7%) later divorced. Life of the other family members was negatively affected in 8 (30.7%). Two donors' spouses (7.7%) failed to carry out domestic responsibilities.
Psychological disturbance and abnormal family functioning are frequently observed during the posttransplant period. Therefore, psychologic assessment and evaluation of family functioning should be regularly repeated during the posttransplant period.
背景/目的：本研究旨在调查活体肝移植供者移植前后的临床和心理社会特征，以及活体亲属肝移植的影响和可能影响心理社会结局及家庭功能的相关因素。
对32名活体供者（19名女性，年龄31.84±7.10岁）进行了评估。评估了供者移植前后临床和心理特征以及家庭生活的医疗记录。
大多数供者是父母（n=28，87.6%）。在移植前评估中，5名供者（19.3%）对术后并发症和生活质量感到焦虑。供者中位出院时间为7天（范围5 - 30天）。恢复工作和完全恢复良好感觉的中位时间分别为4周（范围1 - 32周）和10周（范围4 - 48周）。16名受者（50.0%）出现严重并发症，3名（9.4%）需要侵入性干预。14名供者（43.4%）术后报告手术切口周围疼痛和非特异性胃肠道问题。8名供者（25.0%）出现心理问题；2名（6.3%）患有抑郁症，需要药物和心理治疗干预。发现心理障碍与受者存在问题相关（p<0.01，r=0.487）。供者与受者的关系在1例中受到负面影响（3.1%），但在15例中得到改善（46.9%）。9名供者（34.6%）对配偶表现出紧张行为，2名（7.7%）后来离婚。其他家庭成员的生活在8例中受到负面影响（30.7%）。2名供者的配偶（7.7%）未能履行家庭责任。
移植后期间经常观察到心理障碍和家庭功能异常。因此，移植后期间应定期重复进行心理评估和家庭功能评价。
