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比较阴道脱垂手术后不完全排空时清洁间歇性导尿和经尿道留置导尿:一项多中心随机试验。

Comparing clean intermittent catheterisation and transurethral indwelling catheterisation for incomplete voiding after vaginal prolapse surgery: a multicentre randomised trial.

机构信息

Department of Obstetrics and Gynaecology, Spaarne Hospital, Hoofddorp, the Netherlands.

出版信息

BJOG. 2011 Aug;118(9):1055-60. doi: 10.1111/j.1471-0528.2011.02935.x. Epub 2011 Apr 11.

DOI:10.1111/j.1471-0528.2011.02935.x
PMID:21481147
Abstract

OBJECTIVE

To compare clean intermittent catheterisation with transurethral indwelling catheterisation for the treatment of abnormal post-void residual bladder volume (PVR) following vaginal prolapse surgery.

DESIGN

Multicentre randomised controlled trial.

SETTING

Five teaching hospitals and one non-teaching hospital in the Netherlands.

POPULATION

All patients older than 18 years experiencing abnormal PVR following vaginal prolapse surgery, with or without the use of mesh. Exclusion criteria were: any neurological or anxiety disorder, or the need for combined anti-incontinence surgery.

METHODS

All patients were given an indwelling catheter directly after surgery, which was removed on the first postoperative day. Patients with a PVR of more than 150 ml after their first void were randomised for clean intermittent catheterisation (CIC), performed by nursing staff, or for transurethral indwelling catheterisation (TIC) for 3 days.

MAIN OUTCOME MEASURE

Bacteriuria rate at end of treatment.

RESULTS

A total of 87 patients were included in the study. Compared with the TIC group (n = 42), there was a lower risk of developing bacteriuria (14 versus 38%; P = 0.02) or urinary tract infection (UTI; 12 versus 33%; P = 0.03) in the CIC group (n = 45); moreover, a shorter period of catheterisation was required (18 hours CIC versus 72 hours TIC; P < 0.001). Patient satisfaction was similar in the two groups, and no adverse events occurred.

CONCLUSION

Clean intermittent catheterisation is preferable over indwelling catheterisation for 3 days in the treatment of abnormal PVR following vaginal prolapse surgery.

摘要

目的

比较清洁间歇性导尿与经尿道留置导尿治疗阴道膨出手术后异常的剩余膀胱量(PVR)。

设计

多中心随机对照试验。

地点

荷兰五所教学医院和一所非教学医院。

人群

所有年龄大于 18 岁的患者,在阴道膨出手术后有异常 PVR,无论是否使用网片。排除标准为:任何神经或焦虑障碍,或需要联合抗失禁手术。

方法

所有患者在手术后立即留置导尿管,术后第一天拔除。首次排空后 PVR 超过 150ml 的患者随机分为清洁间歇性导尿(CIC)组,由护理人员进行,或经尿道留置导尿(TIC)组,留置 3 天。

主要观察指标

治疗结束时的菌尿率。

结果

共有 87 例患者纳入研究。与 TIC 组(n=42)相比,CIC 组(n=45)发生菌尿的风险较低(14%比 38%;P=0.02)或尿路感染(UTI;12%比 33%;P=0.03);此外,导尿管留置时间也较短(18 小时 CIC 比 72 小时 TIC;P<0.001)。两组患者的满意度相似,且均未发生不良事件。

结论

与经尿道留置导尿 3 天相比,清洁间歇性导尿治疗阴道膨出手术后异常 PVR 更为可取。

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