Critical Care, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, UK.
J Hosp Infect. 2011 Aug;78(4):302-7. doi: 10.1016/j.jhin.2011.02.009. Epub 2011 Apr 9.
West Midlands was particularly affected by the 2009 H1N1 influenza A (pH1N1) pandemic. Vaccination of frontline healthcare professionals (HCPs) aimed to prevent spread to vulnerable patients, minimise service disruption and protect staff. HCPs involved in upper airway management are particularly at risk of aerosol exposure. We assessed the attitudes of these HCPs towards pandemic influenza A (H1N1) 2009 vaccination uptake: primary reasons for acceptance, barriers to vaccination, and knowledge surrounding pH1N1 influenza. We performed a voluntary, anonymous questionnaire survey based in two West Midlands National Health Service Trusts, one month after introduction of the vaccine. In all, 187 useable responses were received (60.5% response rate); 43.8% (N=82) had/intended to receive vaccination. Concern over long term side-effects was the main deterrent (37.4%, N=70). Primary reasons for potentially accepting vaccination were: to protect themselves (36.9%, N=69), to protect family (35.3%, N=66), and to protect patients (10.2%, N=19). Of responders, 76.5% were unsure that the vaccines had undergone suitably rigorous clinical trials to ensure safety; 20.9% correctly identified reported vaccine efficacy. We conclude that pH1N1 vaccination uptake among high risk HCPs remained low, although twice that of peak seasonal influenza vaccination rates. HCPs' knowledge of vaccine efficacy is poor. Barriers to vaccination include concerns over safety profile given the short chronological time-span between the pandemic being declared and vaccine introduction. Side-effects, both acute and chronic, are a significant barrier to vaccination. Further reassurance/education surrounding vaccine safety/efficacy at the time of any future pandemic may improve uptake rates.
西米德兰兹地区受 2009 年 H1N1 甲型流感（pH1N1）大流行的影响尤为严重。为了防止病毒传播给弱势患者、尽量减少服务中断并保护医护人员，前线医护人员（HCPs）需要接种疫苗。涉及上呼吸道管理的 HCPs 尤其有暴露于气溶胶的风险。我们评估了这些 HCPs 对 2009 年甲型流感大流行（H1N1）疫苗接种的态度：接受疫苗接种的主要原因、接种疫苗的障碍以及围绕 pH1N1 流感的知识。我们在西米德兰兹的两家国民保健服务信托基金中进行了一项自愿、匿名的问卷调查，调查是在疫苗推出一个月后进行的。共收到 187 份有效回复（60.5%的回复率）；43.8%（N=82）已经/打算接种疫苗。对长期副作用的担忧是主要的阻碍因素（37.4%，N=70）。潜在接受疫苗接种的主要原因是：保护自己（36.9%，N=69）、保护家人（35.3%，N=66）和保护患者（10.2%，N=19）。在回答者中，76.5%的人不确定疫苗是否经过了严格的临床试验以确保安全性；20.9%的人正确识别了报告的疫苗效力。我们得出结论，高危 HCPs 中的 pH1N1 疫苗接种率仍然很低，尽管是季节性流感疫苗接种率峰值的两倍。HCPs 对疫苗效力的了解很差。接种疫苗的障碍包括在宣布大流行和推出疫苗之间的时间跨度很短，对安全性的担忧。副作用，无论是急性还是慢性，都是接种疫苗的一个重大障碍。在未来任何大流行期间，围绕疫苗安全性/效力进行进一步的保证/教育可能会提高接种率。
