Department of Plastic and Reconstructive Surgery, Royal Preston Hospital, Sharoe Green Lane, Preston PR29HT, United Kingdom.
J Plast Reconstr Aesthet Surg. 2011 Jul;64(7):e170-3. doi: 10.1016/j.bjps.2011.03.009. Epub 2011 Apr 9.
Cyanoacrylate is the generic name for cyanoacrylate based 'fast-acting' adhesives such as methyl-2-cyanoacrylate and ethyl-2-cyanoacrylate(commonly sold under trade names like Super Glue and Krazy Glue). Other forms have been developed as medical grade glues to be non-toxic and less irritating to skin tissue. Cyanoacrylate has a multitude of uses, ranging from simple domestic applications, to those for industrial purposes. It is an acrylic resin which rapidly polymerises in the presence of water (specifically hydroxide ions), forming long, strong chains, joining the bonded surfaces together. Cyanoacrylate sets quickly, often in less than a minute and a normal bond reaches full strength in two hours and is waterproof. This case report outlines an interesting case of a full thickness burn resulting from skin in contact with cyanoacrylate glue, including highlighting several areas where the management was not appropriate. This was likely due to the novel presentation of this patient, and lack of education of staff. Although there have been cases of burns resulting from this type of glue documented in the literature, there are none of this exact nature and depth. [See figure in text]. Polymerization of methyl-2-cyanoacrylate.
氰基丙烯酸酯是基于氰基丙烯酸酯的“快速作用”粘合剂的通用名称，例如甲基-2-氰基丙烯酸酯和乙基-2-氰基丙烯酸酯（通常以超级胶水和疯狂胶水等商品名出售）。已经开发出其他形式的医用级胶水，以使其对皮肤组织无毒且刺激性较小。氰基丙烯酸酯具有多种用途，从简单的家庭用途到工业用途。它是一种丙烯酸树脂，在水（特别是氢氧化物离子）的存在下迅速聚合，形成长而强的链，将粘合表面连接在一起。氰基丙烯酸酯会迅速凝固，通常在不到一分钟的时间内，正常的粘合在两小时内即可达到完全强度，并具有防水性。本病例报告概述了一例因皮肤接触氰基丙烯酸酯胶而导致全层烧伤的有趣病例，包括突出了几个管理不当的方面。这可能是由于该患者的新颖表现以及工作人员缺乏教育所致。尽管文献中有因这种类型的胶水而导致烧伤的病例，但没有一例具有这种确切性质和深度。[见图]。甲基-2-氰基丙烯酸酯的聚合。
