Biology Department, University of Massachusetts Amherst, Amherst, MA 01003, USA.
Curr Biol. 2011 Apr 12;21(7):R261-3. doi: 10.1016/j.cub.2011.02.026.
During mitosis the kinetochore assembles on centromeric chromatin. The component that connects the chromatin-associated inner domain to the microtubule-binding outer domain has eluded researchers. Two new studies identify a conserved molecular linkage between the inner and outer kinetochore.
在有丝分裂过程中，动粒组装在着丝粒染色质上。将与染色质相关的内域连接到微管结合的外域的组件一直困扰着研究人员。两项新的研究确定了内动粒和外动粒之间的保守分子连接。
