University of Helsinki, Department of Environmental Sciences, Lahti, Finland.
Ecotoxicol Environ Saf. 2011 Jul;74(5):1151-5. doi: 10.1016/j.ecoenv.2011.03.017. Epub 2011 Apr 9.
The linkage between acute adverse effects of cadmium and internal cadmium levels were investigated for the oligochaete worm Lumbriculus variegatus in water at varying degrees of hardness and two different dissolved organic carbon (DOC) concentrations. The LC₅₀s for the effect of cadmium on the survival of the worms greatly differed depending on water hardness and DOC. We found less variability in internal metal toxicity metrics (lethal residue; LR₅₀s) than in external toxicity metrics (lethal concentration; LC₅₀s): LC₅₀s varied from 2.4 to 66.1 μmol/L, while LR₅₀s varied only from 226 to 413 μmol/kg wet weight. The cadmium body burden appeared to be independent of exposure conditions. From our experimental data, a critical cadmium body residue (324 ± 78 μmol/kg wet weight) associated with 50% lethality was derived. The protective role of DOC and water hardness against cadmium toxicity was evident.
研究了在不同硬度和两种不同溶解有机碳 (DOC) 浓度的水中，镉的急性不良反应与体内镉水平之间的关系。镉对蚯蚓存活率的影响的 LC₅₀值因水硬度和 DOC 而有很大差异。我们发现，内部金属毒性指标（致死残留；LR₅₀值）的变异性小于外部毒性指标（致死浓度；LC₅₀值）：LC₅₀值从 2.4 到 66.1 μmol/L 不等，而 LR₅₀值仅从 226 到 413 μmol/kg 湿重不等。镉的体内负荷似乎与暴露条件无关。根据我们的实验数据，得出了一个与 50%致死率相关的临界镉体残留（324 ± 78 μmol/kg 湿重）。DOC 和水硬度对镉毒性的保护作用显而易见。
