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[肺康复计划对慢性阻塞性肺疾病严重程度的影响]

[The effects of a pulmonary rehabilitation program in relation to the severity of COPD].

作者信息

Beaumont M, Reychler G, Le Ber-Moy C, Peran L

机构信息

Service de réhabilitation respiratoire, centre hospitalier des Pays-de-Morlaix, Kersaint Gilly, Morlaix cedex, France.

出版信息

Rev Mal Respir. 2011 Mar;28(3):297-305. doi: 10.1016/j.rmr.2010.09.034. Epub 2011 Mar 12.

Abstract

INTRODUCTION

The aim of this study is to assess the effects of in-patient pulmonary rehabilitation in relation to the stages of COPD according to GOLD and the BODE index.

METHOD

A prospective cohort study over 4 weeks. The 6-minute walk test, the relationship dyspnoea (EVA)/walking distance, dyspnoea (MRC scale), the Saint-George's respiratory questionnaire and the BODE index were estimated at the beginning and end of a pulmonary rehabilitation programme.

RESULTS

Fifty patients with COPD were included, distributed according to GOLD (II: 30%; III: 32%; IV: 38%) and BODE (quartile 1: 22%; quartile 2: 36%; quartile 3: 26%; quartile 4: 16%). All the patients benefited from the programme. For the GOLD classification, there was no significant difference between stages. For the BODE classification, a significant difference existed between quartiles concerning the evolution of dyspnoea (P=0,025), the relationship dyspnoea/walking distance (P<0,001) and BODE index (P<0,001), to the advantage of patients in quartiles 3 and 4.

CONCLUSION

All patients benefit from rehabilitation in hospital; the most severe benefit the most. The BODE index seems to predict those who make the greatest improvement.

摘要

引言

本研究旨在根据慢性阻塞性肺疾病全球倡议(GOLD)和BODE指数评估住院肺康复对慢性阻塞性肺疾病(COPD)不同阶段的影响。

方法

一项为期4周的前瞻性队列研究。在肺康复计划开始和结束时,评估6分钟步行试验、呼吸困难与步行距离的关系(EVA)、呼吸困难(MRC量表)、圣乔治呼吸问卷和BODE指数。

结果

纳入50例COPD患者,根据GOLD分级分布(II级:30%;III级:32%;IV级:38%),根据BODE指数分布(四分位数1:22%;四分位数2:36%;四分位数3:26%;四分位数4:16%)。所有患者均从该计划中受益。对于GOLD分级,各阶段之间无显著差异。对于BODE分级,四分位数之间在呼吸困难的改善(P = 0.025)、呼吸困难与步行距离的关系(P < 0.001)和BODE指数(P < 0.001)方面存在显著差异,四分位数3和4的患者受益更多。

结论

所有患者均从住院康复中受益;病情最严重的患者受益最大。BODE指数似乎可以预测改善最大的患者。

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